Thursday, June 21, 2012

Ear Acupuncture Benefits The Heart – New Research

Researchers have discovered that auricular acupuncture benefits the heart by increasing heart rate variability (HRV). HRV is the body’s ability to regulate the time interval between heart beats and is an index of the body’s ability to maintain control of the heart beat rate andAcupuncture CEU OnlineEar Acupuncture rhythm through vagus nerve activity. A lowering of HRV is found in unhealthy and highly stressed individuals. Acupuncture’s ability to raise HRV is of importance because reduced HRV is linked to mortality after myocardial infarction, congestive heart failure, diabetic neuropathy and low survival rates in premature babies. A reduction of HRV is also common in patients with PTSD (post-traumatic stress syndrome) and for individuals with increased heart rates due to stress.
Acupuncture’s ability to raise HRV was measured using electrocardiograms (ECGs) and an HRV Mediolog AR12 system. The evidence-based research concludes that “HRV changes significantly during auricular acupuncture…” and that “HRV total increases during auricular acupuncture….” The research team, based in China and Austria, measured significant increases in HRV when needling Ear-Shenmen (earpoint: Heart). Ear-Shenmen is located on the external ear at the bifurcating point between the superior and inferior antihelix crus at the lateral third of the triangular fossa. In Traditional Chinese Medicine (TCM), Ear-Shenmen is used for sedation, relaxing the mind, pain relief and clearing the heart.
Researchers from the International Society for Autonomic Neuroscience discovered similar results last year. They measured that needling acupuncture point CV17 increases HRV. They concluded that acupuncture at CV17 “causes the modulation of cardiac autonomic function.” The research measured the mechanism by which acupuncture at CV17 is able to activate the autonomic nervous system to control the heart rate by increasing vagal activity.

Laser Acupuncture Lowers Heart Rate – New Proof

Laser Acupuncture OnlineLaser AcupunctureNew research reveals that ultra-low-level violet laser stimulation of acupuncture point Du-20 (Baihui) changes the heart rate. A 405nm wavelength laser beam at an output power of 1mW (continuous mode) was directed at Du-20 (Baihui, GV-20) on laboratory rats. There was an acute on/off effect when activating the laser beam. When on, the laser beam significantly lowered the heart rate. Results were measured by electrocardiograms using an HRV Medilog AR12 system. The acupuncture point Du-20 was located “at the continuation of the line connecting the highest points of the ear, on the median line of the head.”
The researchers note that laser acupuncture “can modulate physiological and neurovegetative parameters after stimulating the Baihui acupuncture point” and that there was a “clear on/off-effect when the laser was activated/deactivated.” Given the controlled predictability of laser acupuncture stimulation on bodily function, the researchers from the Medical University of Graz, Austria and the Institute of Acupuncture and Moxibustion at the China Academy of Chinese Medical Sciences conclude that low-level laser acupuncture can be used in clinical studies.

MRI Acupuncture Research Maps Brain Network

New MRI research shows that autonomic nervous system (ANS) responses to acupuncture emanate from “distinct subregions” of “brain circuitry." A prestigious team of researchers from institutions such as MIT (Massachusetts Institute of Technology), University of Michigan and Massachusetts General Acupuncture CEUs OnlineAcupuncture MRI ResearchHospital compared true acupuncture at acupoints ST36 and SP9 with sham acupuncture (non-acupoint location). True acupuncture activated the secondary somatosensory cortex (S2), insula, and the mid-cingulate cortex. The heart rate (HR) deceleration and skin conductance response (SCR) “magnitude of response was greater following real acupuncture” than with sham acupuncture.
Differential outflows of autonomic nervous system responses to acupuncture were associated with specific brain responses. Acupuncture with strong SCR causes “greater anterior insula activation” of the brain, particularly at acupoint SP9. Acupuncture stimulation producing greater deceleration of the heart rate was proportional to brain default mode network (DMN) deactivation. DMN is a network of brain areas responsible for internal processing including wakeful resting, memory recall, daydreaming and thinking about the future. ST36 had a significantly strong heart rate reduction and corresponding DMN response.

Acupuncture Treats Atrial Fibrillation – New Research

Acupuncture CEUs OnlineAcupuncture for A-fibNew research concludes that “acupuncture may be an effective non-invasive and safe antiarrhythmic tool” for the treatment of A-fib (atrial fibrillation, AF). A-fib is a common cardiac arrhythmia and is often associated with palpitations, chest pain and syncope. In A-fib, the normal P wave measured with an electrocardiogram is pathologically absent.

The researchers applied acupuncture points P6 (Neiguan), HT7 (Shenmen) and UB15 (Xinshu). Acupuncture was applied once per week for a total of ten weeks. All participants in the study had normal ventricular function. The researchers concluded that acupuncture “was associated with an antiarrhythmic effect.” Notably, true acupuncture was found significantly effective for the treatment of atrial fibrillation and sham acupuncture (non-acupoint) was not. In addition, acupuncture had similar efficacy to amiodarone, an antiarrhythmic pharmaceutical medication, in the prevention of A-fib recurrence. Moreover, acupuncture was effective for the treatment of both persistent and paroxysmal atrial fibrillation

Acupuncture & PEA for Multiple Sclerosis Pain

Acupuncture CEUs OnlineAcupuncture with PEA for MSA recent case study from the Institute for Neuropathic Pain concludes that combining acupuncture with palmitoylethanolamide (PEA) has a synergistic effect in reducing central neuropathic pain for patients with multiple sclerosis (MS). The combination reduces both pain intensity and the duration of pain relief. PEA is an endogenous fatty acid amide and is an endocannabinoid with an affinity for the cannabinoid-like receptors GPR55 and GPR119. Unlike THC (a psychoactive component in marijuana), PEA does not bind to CB1 and CB2 cannabinoid receptors.
The researchers note that acupuncture partially reduced the 61 year old female patient’s pain. After adding PEA to the regime of care, the patient’s pain levels decreased even further than with acupuncture as the only treatment modality. Additionally, the patient needed less frequent acupuncture care when using PEA to help control pain levels. The researchers suggest that a “multimodal stepped care approach is demonstrated” with both acupuncture and PEA affecting activated glial cells, which are important cells in relation to the control of neuropathic pain.

Saturday, June 16, 2012

Acupuncture Stops Dermatitis Itch – New Research

Acupuncture CEUs OnlineAcupuncture for ItchNew research concludes that acupuncture “significantly reduced type I hypersensitivity itch in patients with AD (atopic dermatitis).” In this double-blinded, randomized, placebo-controlled study; researchers compared acupuncture and drug therapy with placebo and non-intervention control groups. Both acupuncture and drug therapy significantly reduced itching with acupuncture being the most effective of the two.
Researchers measured outcomes for two types of acupuncture protocols. Protocol I measured the effects of acupuncture using preventative (preceding) acupuncture treatment. Protocol II measured acupuncture’s effects when applied to active itching. Protocol II was the most effective of the two. Drug therapy testing employed citirzine, an antihistamine, as the pharmacological agent to control itching. Citirizine (Zyrtec, Reactine) was as effective as preventative acupuncture care but not as effective as active acupuncture.

Acupuncture for Osteoporosis - Calcium & Bone New Research

Acupuncture CEUs OnlineAcupuncture for BoneNew research demonstrates that acupuncture with Chinese healing massage improves bone metabolism for the prevention of osteoporosis. Researchers compared sixty-four subjects divided into two groups. Group 1 was administered vitamin D with calcium carbonate in oral tablets for a period of 12 weeks. Vitamin D is an essential component for the proper absorption of calcium. Group 2 received acupuncture at acupoints UB40 (Weizhong) and K3 (Taixi) combined with tuina massage on the lower back. Tuina, literally translated as push and grasp, is a type of Chinese medical massage. Acupuncture was administered a total of 30 times over a period of 12 weeks. Both the oral calcium with vitamin D and acupuncture with tuina groups showed similar improvements in the biochemical indices of bone metabolism related to osteoporosis.
Blood analysis measured increases in levels of BGP (bone gla protein) in both the supplement and acupuncture groups. BGP is an important biomarker of bone metabolism. Higher serum levels of BGP indicate greater bone mineral density. Blood analysis also revealed that both the supplement and acupuncture groups had decreases in levels of phoshphorus and urine deoxypyridinoline (DPD). Higher numbers of DPD in the urine indicates a risk for osteoporosis. DPD provides structural integrity to type 1 collagen in bones. High urine DPD is common in post-menopausal women due to lower levels of estrogen. Although phosphorus is an important bone mineral, excess quantities in relation to calcium intake contribute to bone loss.

Scalp Acupuncture Treats Stroke Hemorrhage – New Research

Acupuncture CEUs OnlineAcupuncture Affects CD4A new acupuncture study reviews the history and research associated with the beneficial effects of scalp acupuncture for the treatment of intracerebral hemorrhage (ICH). The researchers note, “The evidence from clinical studies suggested that SA (scalp acupuncture) therapy may produce significant benefits for patients with acute ICH.” ICH is a potentially life-threatening type of stroke with a higher death rate and higher disability rate than ischemic strokes. Strokes and cerebrovascular disease account for approximately 11 percent of all worldwide deaths annually and is second only to heart disease as a cause of death. The researchers note that studies confirm that scalp acupuncture “has rapid and powerful effects to remove limb paralysis caused either by cerebral infarct or by cerebral haemorrhage in rats.” In human studies, ICH patients showed rapid and beneficial responses to scalp acupuncture and scalp acupuncture increases electrical activity in the brain following ICH.
The researchers investigated the mechanisms by which scalp acupuncture prevents pathophysiological responses due to ICH. CT (computerized tomography) shows that acupuncture at GV20 (Baihui) and Taiyang (EX-HN5) improves the “abosorption rate of hematoma.” Research also shows that scalp points GV20 and GB7 (Qubin) reduce “brain edema.” ICH research shows that acupuncture at GV20, GV26 (Shuigou), LI4 (Hegu), and LR3 (Taichong) accelerates “the extenuation of brain edema and diminish(es) cerebral vessel permeability and brain tissue damage.” The research also demonstrates that electroacupuncture from GV20 to Taiyang promotes tissue repair of the blood-brain barrier.
Research shows that acupuncture at GV20 and Taiyang benefits immune system function with measurable increases in CD3 and CD4 levels. CD3 is required for T-cell activation, a type of white blood cell important in cell-mediated immunity responses. CD4 is a subtype of T-cell known as a Helper T-cell.
The researchers note the ability of scalp acupuncture to prevent deleterious chemical responses in the brain due to ICH. Modern research shows that acupuncture at GV20 and GB7 regulates the expression of brain chemicals including protease-activated receptors (PARs), MMP9 and AQP4. The cellular effects of thrombin are mediated by protease-activated receptors and PARs contribute to pro-inflammatory responses. MMP9 is an enzyme involved in ICH and tissue remodeling. AQP4 is a protein that conducts water through cell membranes and is upregulated by disturbances to the central nervous system.
Research also shows that acupuncture at GV20 and GB7 regulates the cascade of endogenous inflammatory chemicals released after a stroke. These acupuncture points prevent inflammation by inhibiting IL-1beta in the brain tissue region of a hematoma. IL-1beta is a pro-inflammatory cytokine, a cell-signaling protein molecule used in intercellular communication. Also, scalp acupuncture causes a rapid decrease of IL-6 (Interleukin-6), another cytokine involved in the inflammatory response. Left unchecked, IL-6’s pro-inflammatory effects are pathological. IL-6 mediates fevers, crosses the blood-brain barrier and is found in high levels in patients with metastatic cancer.
The researchers note that acupuncture at GV20 and Taiyang has an “inhibitory effect on the immune-inflammatory reaction mediated by TNF-(alpha) expression….” TNF (Tumor Necrosis Factor) is a cytokine that is involved in various biological functions including septic shock and wasting syndrome. Additionally, acupuncture at GV20 and GB7 “promoted heat shock protein 70 (HSP70) mRNA expression in brain tissue….” HSP70’s help cells fold proteins and have the ability to protect cells from stress. Other scalp acupuncture research shows “improved mitochondrial energy metabolism in (the) brain….”
Neuro-electrophysiology scalp acupuncture studies show that that acupuncture at GV20 and Taiyang improves “coordination and compensation functions among cortical functional areas” in ICH patients. Scalp acupuncture has also been shown to beneficially affect the electrical activity of pain-reaction neurons. Also noted, GV20 and GB7 promote the expression of glial cell neurotrophic factor (GDNF). GDNF is a protein that promotes the survival of neurons. Moreover, the researchers note even more biochemical, bioelectrical and biophysiological benefits of scalp acupuncture on brain tissue related to ICH.
History of Scalp Acupuncture
The researchers give an interesting historical account of scalp acupuncture. First recorded in 5 BCE, Bian Que successfully revived the crowned prince of Guo from a near lifeless state using scalp acupuncture. The Huangdi Neijing (Yellow Emperor’s Internal Classic) notes that the head is the: meeting of all Yang meridians, house of the original spirit, convergence between Qi and Blood. Head acupuncture points regulate: Yin and Yang, Qi and Blood, Zang-Fu Organs. The Huangdi Neijing also notes that the brain is the: sea of marrow, master of Zang-fu organs, master of channel function. Scalp acupuncture continued to develop over the years including extensive writings in the Jin Dynasty work, the Zhenjiujiayijing (A-B Classic of Acupuncture and Moxibustion).
Modern History
In the 1970s, scalp acupuncture combined with biomedicine using neuroanatomy, neurophysiology and bioholographic principles. Luminaries such as Jiao Shunfa, Fang Yunpeng, Zhu Longyu, Zhang Mingjiu, Tang Songyan, Dr. Toshikatsu Yamamoto and Lin Xuejian contributed to the early development of this integrated form of scalp acupuncture. Prof. Mingqing Zhu began developing what is now a highly regarded system of scalp acupuncture in the 1970s and published his successes in journals and books. Prof. Mingqing Zhu developed a zone system of scalp acupuncture and incorporated advanced needling techniques into this system. He brought the system to the United States and opened scalp acupuncture centers in Santa Cruz, San Jose and San Francisco, California. Today, many practitioners use at least one of eight different styles of scalp acupuncture in clinical practice.

First Ever Acupuncture COPD Trial

The very first placebo-controlled, randomized study on the effectiveness of acupuncture for the treatment of chronic obstructive pulmonary disease (COPD) concludes “that acupuncture is a useful adjunctive therapy in reducing” breathlessness in patients with COPD. A decrease in shortness of breath in patients with COPD is directly proportional to increased survival rates indicating that acupuncture prevents mortality associated with COPD. The researchers note that acupuncture improved arterial blood gas, rib cage range of motion, respiratory function (including forced vital capacity) and respiratory muscle strength. The ability to increase exercise capabilities was also greatly increased by acupuncture treatment. Moreover, acupuncture improved the activities of daily living score. In addition, acupuncture significantly improved nutritional levels including BMI (body mass index) and pre-albumin levels, common major nutritional problems for patients with COPD.
Acupuncture CEUs OnlineAcupuncture for COPDA placebo acupuncture group was compared with a real acupuncture group. The placebo group received simulated needling using a Park sham device. The device uses a blunt tipped needle that looks as if it is penetrating the skin but, in reality, telescopes back into the upper part of the needle handle. Both the sham needle and the real needles were 0.35mm X 70mm stainless steel acupuncture needles. The real acupuncture needles were inserted between 5mm to 25mm. Electroacupuncture was not used and manual rotation stimulation was performed at each needle for 3-5 minutes until the de qi sensation was achieved. Total treatment time was 50 minutes for each treatment. Acupuncture treatments were administered once per week for a total of 12 weeks. The acupuncture points chosen for the study were: LU1 (Zhongfu), LU9 (Taiyuan), LI18 (Futu), CV4 (Guanyuan), CV12 (Zhongwan), ST36 (Zusanli), KI3 (Taixi), GB12 (Wangu), UB13 (Feishu), UB20 (Pishu), UB23 (Shenshu). The researchers note, “We demonstrated clinically relevant improvements in DOE  (dyspnea on exertion) (Borg scale), nutrition status (including BMI), airflow obstruction, exercise capacity, and health-related quality of life after 3 months of acupuncture treatment.”
Points of Interest
Interestingly, the researchers did not use Dingchuan (M-BW-1). This modern ‘extra’ acupuncture point is specific for the treatment of dyspnea, wheezing and coughing. Dingchuan is also used for the treatment of urticaria and upper back pain.
The researchers chose LU1 (Middle Palace). Located on the lateral aspect of the chest in the first intercostal space, LU1 is the Front Mu point of the Lung and is the Meeting Point of the Lung and Spleen channels. The other Lung channel point used in the study was LU9 (Supreme Abyss). Located at the wrist joint in the depression between the radial artery and the tendon of  the abductor pollicis longus, LU9 is the Yuan-Source  point of the Lung channel. It is also an Earth point, a Shu-Stream point, and a Hui-Meeting point. LU1 helps the Stomach Qi descend, clears heat, regulates water passages and relieves coughing and wheezing by helping the Lung Qi to descend. LU9 tonifies the Lungs, transforms phlegm, regulates the vessels and relieves pain.
LI18 (Support the Prominence) is located on the lateral aspect of the neck, level with the tip of the Adam’s Apple and is between the heads of the SCM (sternocleidomastoid) muscle. LI18 is a Window of Sky point and relieves coughing, wheezing, dysphagia, throat pain and hypotension.  CV4 (Gate of Origin) and CV12 (Middle Cavity) are the Front Mu points of the Small Intestines and Stomach respectively. These powerful points tonify Qi as does ST36 (Leg Three Miles). Additional points used in the study were used to benefit Lung function and to harmonize and strengthen the body.

iPhone & iPad App Measures Acupuncture Stress Reduction

The SweetBeat App for the iPhone and iPad has the ability to measure stress reduction as a result of acupuncture treatments. This App measures both the heart rate and HRV (heart rate variability). HRV measures the change in time interval between heart beats and is an index of the body’s ability to maintain control of the heart beat rate and rhythm through vagus nerve activity. Reduced HRV is linked to mortality after myocardial infarction, congestive heart failure and diabetic neuropathy.
HRV and Health
Acupuncture AppAcupuncture AppNew research on acupuncture points CV17 and Ear Shenmen shows that acupuncture benefits the heart by increasing heart rate variability (HRV). The SweetBeat App places a valuable measurement tool in the hands of the acupuncturist and the patient. Patients can measure HRV while walking, running, bicycling, at rest, before and after an acupuncture treatment, etc…. If the HRV dips unusually low, this is a serious indication of a potential cardiovascular disturbance. By contrast, the health benefits of a proper regime of dietary changes, exercise, relaxation techniques and acupuncture can be seen in an increase in HRV.

Feature Set

The SweetBeat App has many features including the ability to measure a person’s baseline level of stress. A visual readout is displayed and the user sees whether or not they are stressing their system. This can be invaluable for users who tend to overstress their bodies during workouts or through emotional stress. The App also has functions which allow the user to work on breathing evenly to reduce bodily stress. In addition, the user can save and track changes in HRV over time.
Evaluation
What we find incredibly valuable is the ability of this App to measure both HRV and heart rate. We like the stress indicator because it has an easy visual clue when to back-off from excessive exercise or emotional strain. To use this App, all one needs is a heart rate monitor strap and a dongle to transfer the information to an iPhone or iPad. For our review testing, we used a 60beat brand chest strap and receiver. The receiver plugs into the headphone jack and receives the 5.3KHz data from the chest strap.
How it Works
We simply put on the chest strap, plugged the receiver (dongle) into the iPhone (or iPad) and launched the SweetBeat App. For the initial use, SweetBeat asks the user to set a baseline level of heart performance to help in the analysis of mood and stress levels. The 60beat brand receiver works relatively well and is reliable up to about arms length. This worked well for our testing purposes because our users experimented with various workout speeds on a Stairmaster brand machine and arms length is ample.
Testing
We tested the device and find it very accurate. Both heart rate and HRV are highly responsive and SweetBeet is accurate to the tenths decimal place. As the user increases physical stress, the stress monitor tracked this performance issue with a colored bar graph. At first, we weren’t sure if the stress meter would be valuable. Once in a workout, however, the quick reference of the stress meter is nice addition. It gives valuable feedback without distracting the user from the workout.
Thoughts
This type of device helps the user learn about their heart. It can easily detect forms of heart disease and warns the user of excessive stress during exercise with its easy-to-read visual display. For athletes, sustained increases in HRV over time reflect higher performance levels and proper training. As a result, this is valuable for athletes in training as well as for those just beginning an exercise program. For users who are genuinely interested in tracking their cardiovascular health, we recommend this App. Heart disease is the number one killer worldwide and the SweetBeat App is an affordable tool to monitor one’s most important muscle- the heart.

Acupuncture Education & Treatment Strategy for Prostatitis

Acupuncture CEUs OnlineAcupuncture for ProstateResearchers have published clinical strategies for acupuncture in the study and treatment of nonbacterial prostatitis. Professors from the Guangzhou University of Chinese Medicine (Department of Acupuncture and Moxibustion, Shenzhen Traditional Chinese Medicine Hospital) note that chronic nonbacterial prostatitis (CNP) responds to acupuncture treatment as demonstrated in modern research.1 The publication outlines the underlying theory, treatment principles and optimal acupuncture points for the treatment of CNP.
The professors note that chronic nonbacterial prostatitis involves Kidney deficiency, damp-heat and Blood stasis. Of note, the Kidney, Bladder, Triple Burner, Liver, Spleen and Lung Zang-Fu organs are important in the treatment of prostatitis. From a channel perspective, the researchers note that the Conception Vessel (Ren Mai), Thoroughfare Vessel (Chong Mai), Governing Vessel (Du Mai), Kidney channel, Bladder channel and Liver channel are closely related to prostatitis. They note several common treatment principles used in the treatment of CNP: eliminate blood stasis, clear heat, expel dampness, soothe Liver Qi, unblock collaterals and meridians. They cite several application methods that have significant clinical efficacy: electroacupuncture, laser acupoint irradiation, warm needling acupuncture, moxibustion, herbal injections. Acupuncture points Guanyuan (CV4), Zhongji (CV3), Qugu (CV2), Ciliao (UB32), Yinlingquan (SP9), Sanyinjiao (SP6), Taichong (LR3), Taixi (KI3), and Zhibian (BL54) are noted as both important and ubiquitous in the treatment of CNP. The professors emphasize the arrival of de qi at the acupuncture points with conduction of sensation to the lower abdomen and perineum as important components of the treatment procedure. Acupuncture points (HT7), Sishenchong (EX-HN1) and Neiguan (PC6) are recommended for the treatment of the psychological side effects associated with CNP.

Oxygen Higher at Acupuncture Points – New Research

New research has discovered that oxygen levels are higher at acupuncture points. Using a 25 micron amperometric oxygen microsensor, researchers measured the partial oxygen pressure of the distal left Acupuncture CEUs OnlineAcupuncture pO2forearm of humans. Oxygen levels were significantly higher at the acupuncture points in the measured region: LU9 (Taiyuan), LU8 (Jingqu), PC7 (Daling), PC6 (Neiguan), HT7 (Shenmen), HT6 (Yinxi), HT5 (Tongli), and HT4 (Lingdao). The researchers note that this correlation provides information on the physiology of acupuncture points.
The researchers conducted this human study after a clinical investigation of rabbits measured higher partial oxygen pressure at acupuncture points ST36, ST37, CV16 and CV17 compared with the surrounding regions of the acupoints. The researchers note that their human study uses tiny oxygen sensors and is therefore noninvasive. In addition, they conclude that this research provides “clearer evidence on the strong pO2 (partial oxygen pressure)-acupuncture point correlation….” The researchers note that their investigation may “verify the physical existence of acupuncture points….”

Acupuncture Ups Fertility & Pregnancy Rates – New Research

New research demonstrates higher ovulation and pregnancy rates for women receiving acupuncture combined with clomiphene (clomifert, clomid) compared with women receiving clomiphene only. Clomiphene is a selective estrogen receptor modulator. It inhibits hypothalamus feedback to stimulate production of gonadotropins, hormones that affect fertility Acupuncture CEUs OnlineAcupuncture Fertilityincluding FSH (follicle stimulating hormone) and LH (luteinizing hormone).
The study measured a control group of 19 women and an acupuncture group of 17 women. The control group received 50mg of oral clomiphene at a rate of once per day for a total of 50 menstrual cycles. The acupuncture group received the clomiphene at the same dosage and rate plus regular acupuncture treatments. The researchers measured changes in ovulation, endometrial thickness, cervical mucus, pelvic fluid, and follicular development. The acupuncture group showed a significantly higher rate of both ovulation and conception than the group receiving medication only.
More Recent Studies
In a recent study of 5,807 women, it was demonstrated that acupuncture improves clinical pregnancy rates and live birth rates for women receiving IVF (in vitro fertilization).
A study published in the American Journal of Reproductive Immunology shows that the application of acupuncture to acupoints ST36 and SP6 was shown to prevent egg implantation failure.
In a study of 309 women, it was found that electroacupuncture “significantly improved the clinical outcome of ET (embryo transfer).”
A recent study measured the biochemical mechanisms by which acupuncture increases IVF success rates. In a randomized controlled study, it was concluded that, “Acupuncture could improve the poor receptive state of (the) endometrium due to mifepristone by promoting Th2 cytokines secretion and inhibiting Th1 cytokines to improve blastocyst implantation.”

A Case for Acupuncture Treating Raynaud’s Pain

A case history published in Acupuncture in Medicine investigated acupuncture for the treatment of Raynaud’s phenomenon. The researchers concluded that acupuncture reduced the patient’s pain intensity levels, decreased stiffness of the joints and Acupuncture CEUs OnlineAcupuncture for Raynaud'snormalized the color of the patient’s fingers and toes. Raynaud’s phenomenon comprises both Raynaud’s disease (idiopathic) and Raynaud’s syndrome (secondary). Raynaud’s phenomenon (RP) is a vasospastic disorder that causes discoloration of the fingers, toes and other regions. RP is due to excess sympathetic nerve system stimulation leading to excess vasoconstriction. The consequent hypoxia causes discoloration and sometimes pain, swelling, ulceration or necrosis. Exposure to cold exacerbates the condition and warmth tends to relieve the symptoms.
Acupuncture was applied to a woman, thirty years of age, who suffered from pain and stiffness of the extremities from Raynaud’s disease. Acupuncture was applied to acupoint LI4 (Hegu) bilaterally. The acupuncture was applied for a total of five minutes at a rate of two times per week over a period of two months. The researchers note that a measurement of the patient’s serum proinflammatory cytokines suggests an anti-inflammatory effect from the acupuncture treatments. The researchers concluded that acupuncture “should be considered as an alternative treatment or non-pharmacological therapy for pain associated with RP (Raynaud’s phenonmenon).”

New Acupuncture Magnetoencephalography Results

Researchers measured brain responses to acupuncture with magnetoencephalography (MEG) and concluded that acupuncture induces specific responses to brain Regions of Interest (ROIs). Researchers took MEG measurements of the frontal, central, temporal, parietal and occipital regions of the brain while study participants were needled at acupuncture point ST36 (Zusanli). The Acupuncture CEUs OnlineAcupuncture MEGcontrol group received acupuncture needle stimulation at a nearby non-acupuncture point. The researchers discovered that, “Significantly increased delta power and decreased alpha as well as beta power in bilateral frontal ROIs were observed following stimulation at ST36.”
MEG and Brain Waves
MEG maps brain activity by measuring naturally occurring magnetic fields in the brain, which are produced by electric currents produced by the brain. Alpha waves are neural oscillations in the 8-12 Hz range. These brain waves occur during wakeful relaxation with the eyes closed.
Alpha Waves
Alpha waves diminish with the eyes open, during drowsiness and sleep. Alpha waves are thought to be related to visual cortex activity and to play a role in network coordination and communication. Alpha wave intrusion is the appearance of alpha waves during non-REM sleep, a time when delta wave activity is normally dominant. Alpha wave intrusion is commonly found in patients with chronic fatigue and may be associated with fibromyalgia.
Beta Waves
Beta waves are between 12 – 30 Hz. Beta waves occur during waking consciousness. Beta waves occur in conjunction with muscle contractions during isotonic movements.
Delta Waves
Delta waves are between 0 – 4 Hz. Delta waves have the highest amplitude of the brain waves. Delta waves appear in stage three sleep and are predominant in stage four of sleep. Delta waves stimulate the release of growth hormone releasing hormone (GHRH) and prolactin (PRL). Delta waves inhibit thyroid stimulating hormone (TSH). Disruption of delta wave sleep contributes to type II diabetes. Delta wave disruption by alpha waves is connected with fibromyalgia and poor quality of sleep.

Acupuncture Protects from Liver Fibrosis – New Research

recent study concludes that acupuncture significantly relieves hepatic fibrosis. A study of carbon tetrachloride induced hepatic fibrosis in laboratory rats measured responses to acupuncture treatment. The acupuncture group received acupuncture at LR3 (Taichong), LR14 (Qimen), UB18 (Ganshu), and ST36 (Zusanli). The Acupuncture CEUs OnlineAcupuncture for Livercontrol group received sham acupuncture, the use of non-acupuncture points. The sham acupuncture points were located 0.5cm to the left of each real point that was used in the acupuncture group. No significant changes were measured for the sham group while the true acupuncture group showed significant hepatoprotective findings.
The acupuncture and control groups received acupuncture treatment three times per week for three weeks followed by two times per week for an additional three weeks. The acupuncture group showed significant amelioration from liver injury upon examination of hepatocyte arrangement, necrosis and hepatic pseudo-lobular formation. MMP-9 protein expression levels of hematopoietic stem cells (HSC) were “upregulated remarkably in the acupuncture group” compared with the sham group. MMP-9 (matrix metallopeptidase) is an enzyme that breaks down extracellular matrix and is involved in tissue remodeling. Also, the acupuncture group showed additional significant changes related to the alleviation of liver fibrosis including changes in collagen, fibronectin proteins, TIMP-1 (a tissue inhibitor of metalloproteinases), serum hyaluronic acid and laminin, and several other endogenous secretions.

Acupuncture Points to Different Sides – New Research

New research investigated the effects of needling the same acupuncture point on the left-side versus the effects of needling the acupoint on the right-side to determine if there were any physiological differences. Researchers measured the mean blood flux (MBF) in the acupuncture point LI4 (Hegu) using a Moor full-field laser perfusion imager. The study measured the results of needling LI4 on 120 human volunteers.
Methodology
The acupuncture group received acupuncture at LI4 with a 0.25 X 25mm needle to a depth of 15mm. Manual stimulation to the needle was applied with the rotation method every five minutes for a total of 30 minutes. In the control group, subjects did not receive acupuncture.
Acupuncture Affects Opposite Side
Acupuncture stimulation of right-sided LI4 caused strong amplification of the mean blood flux on the left-sided LI4. However, needling of left-sided LI4 only caused moderate amplification on both sides. The researchers concluded that the acupuncture point LI4 has lateralized specificity.
More Specificity Research
Acupuncture CEUs OnlineAcupuncture at LI4Researchers from the University of California, School of Medicine in Irvine, California concluded, “Recent evidence shows that stimulation of different points on the body causes distinct responses in hemodynamic, fMRI and central neural electrophysiological responses.” MRI results showed that “stimulation of different sets of acupoints leads to disease-specific neuronal responses, even when acupoints are located within the same spinal segment.”
 New MRI research demonstrates that acupuncture “induce(s) different cerebral glucose metabolism changes in pain-related brain regions and reduce(s) intensity of pain” for patients with migraines. The choice of acupuncture points determined specific changes in brain glycometabolism, indicating point specificity.
 New research published in the American Journal of Chinese Medicine concludes that acupuncture at acupoint SP9 (Yinlingquan) increases blood flow/perfusion to the spleen and acupuncture at acupoint LV8 (Ququan) increases blood flow/perfusion to the liver. The researchers concluded, “These results provide scientific evidence of the specificity of meridians.”
A recent MRI study compared brain activity from needling acupoint SP6 with a sham point. SP6 increased activity in the inferior parietal lobe, fusiform temporal gyrus and medial frontal gyrus. The sham point did not activate the areas but instead enhanced activity in the precuneus, a part of the superior parietal lobe. The researchers concluded that true acupuncture affects brain activity differently than needle stimulation at non-acupuncture points.
 A recent study concludes, “Acupuncture is effective in the treatment of functional dyspepsia, and is superior to non-acupoint puncture. The benefit of acupuncture relies on acupoint specificity.” The control group sham points were ineffective in the treatment of dyspepsia whereas the use of Stomach channel acupoints had over a 70 percent success rate.
New research published in the Journal of Magnetic Resonance Imaging demonstrates the point specific neurophysiological effects of acupuncture using MRI technology. Stimulation of acupuncture point GB40 (Qixu) enhanced “connectivity between the superior temporal gyrus (STG) and anterior insula.” Acupuncture point K3 (Taixi) increased the connection strength between the STG and the postcentral gyrus. The researchers concluded that, “The current study demonstrates that acupuncture at different acupoints could exert different modulatory effects on RSNs (brain Resting State Networks). Our findings may help to understand the neurophysiological mechanisms underlying acupuncture specificity.”

Acupuncture Halts Cocaine Addiction – New Research

New research investigated the ability of acupuncture to prevent the relapse of cocaine addiction. A study of cocaine addicted lab rats discovered that those receiving acupuncture at acupoint HT7 (Shenmen) had a “markedly reduced reinstatement of cocaine-seeking” with an 86.5 percent successful inhibition rate.
The researchers note that, “acupuncture reduces drug self-administration and dopamine release in the nucleus accumbens (NAc), a brain structure implicated in stress-induced reinstatement of drug-seeking behavior.” The NAc is an area of the brain important to motor function, rewards and emotions. Dopamine, glucocorticoids, GABA and serotonin play important roles in the NAc.
Using footshock stress to re-stimulate cocaine addiction behavior, researchers applied acupuncture to acupoint HT7 (Shenmen) for one minute following footshock stress to a control group and an acupuncture group. For the control group, footshock stress reinstated cocaine addiction behaviors. In the acupuncture group, there was an 86.5 percent inhibition rate of cocaine addiction. As a result of biochemical measurements taken during the study, the researchers note that the mechanism by which acupuncture prevents cocaine addiction relapse may be due to the ability of acupuncture to regulate “neuronal activation in the NAc shell.”
Acupuncture CEUs OnlineEar AcupunctureA mounting body of evidence supports this new research. A great deal of interest was stimulated twelve years ago when Yale University researchers concluded that auricular acupuncture was effective in the treatment of cocaine addiction. The results of the study, published in the Archives of Internal Medicine, showed that the acupuncture group tested 54.8 percent free of cocaine while the two control groups were 23.5 percent and 9.1 percent free of cocaine at the end of the study. In addition, a lower recidivism rate was measured in the acupuncture group.

Acupuncture Relieves Lower Back Pain – New Research

A new study of 236 patients published in the Journal of Musculoskeletal Pain concludes that acupuncture is an effective treatment modality for the relief of lower Acupuncture CEUs OnlineAcupuncture at LI4back pain. A total of 14 acupuncture treatments were applied over a period of four weeks in this randomized investigation. The researchers concluded that acupuncture has “beneficial and persistent effectiveness against CLBP (chronic lower back pain).”
In related research, acupuncture at acupoint LI4 (Hegu) was found to help in the relief of lower back pain. A group of 187 patients with CLBP received 18 treatments over a period of 7 weeks in this controlled clinical trial. Two separate acupuncture groups, one using LI4 and one not using this acupoint in the prescription, showed statistically significant relief from lower back pain.
The LI4 acupuncture point findings are consistent with acupuncture theory. LI4 is known for its pain relieving effects (including the neck, head, face and upper limbs) along with other points located on the hand. Yaotongxue, located on the dorsum of the hand, is a common acupuncture point used in the treatment of acute lumbar strain. Its lower back pain relieving effects are often immediate with lasting results.

University of Maryland Acupuncture Research – It Works!

A collaborative investigation between researchers from the University of Maryland School of Medicine (Baltimore) and the Shanghai University of Traditional Chinese Medicine concludes that, “Recent clinical trial and systematic review results clearly show acupuncture to be more beneficial Acupuncture CEUs OnlineAcupuncture Researchthan conventional standard care for many pain conditions….” Published in Medical Acupuncture, the review notes that basic science research has identified several mechanisms by which acupuncture exerts its effectiveness in the treatment of pathological conditions. The authors note that “an extensive body of acupuncture research has been published, much of it with important clinical implications.” In addition, the authors note that there is a trend towards acupuncture becoming accepted by the mainstream in the United States, citing a national survey showing a growth in acupuncture utilization.
Recent Research Topics
The modern research continues to pour in. Below is a short list of some of the research that has sparked recent interest. The list is by no means exhaustive and new research continues to map the neurophysiological mechanisms of acupuncture.
Liver Fibrosis
A recent sham-controlled study measured the mechanisms by which acupuncture prevents liver fibrosis. Acupuncture demonstrated changes to hepatocyte arrangement and relief from necrosis and hepatic pseudo-lobular formation. Also, MMP-9 protein expression levels of hematopoietic stem cells (HSC) were “upregulated remarkably” by the use of acupuncture.
Brain Waves
Magnetoencephalography (MEG) demonstrated that acupuncture induces specific responses to brain waves. Researchers discovered that, “Significantly increased delta power and decreased alpha as well as beta power in bilateral frontal ROIs (brain Regions of Interest) were observed following stimulation at ST36.”
Fertility
A recent study measured the biochemical mechanisms by which acupuncture increases IVF success rates. In a randomized controlled study, it was concluded that, “Acupuncture could improve the poor receptive state of (the) endometrium due to mifepristone by promoting Th2 cytokines secretion and inhibiting Th1 cytokines to improve blastocyst implantation.”
Oxygen at Points
New research has discovered that oxygen levels are higher at acupuncture points. The researchers note that their investigation may “verify the physical existence of acupuncture points….”
Osteoporosis
New research demonstrates that acupuncture improves bone metabolism for the prevention of osteoporosis. Blood analysis measured increases in levels of BGP (bone gla protein) from acupuncture treatment.
MRI Investigation
Researchers from MIT (Massachusetts Institute of Technology, Cambridge) and the University of Michigan (Ann Arbor) utilized MRI research to demonstrate that autonomic nervous system (ANS) responses to acupuncture emanate from “distinct subregions” of “brain circuitry.” True acupuncture activated the secondary somatosensory cortex (S2), insula and the mid-cingulate cortex. The heart rate (HR) deceleration and skin conductance response (SCR) “magnitude of response was greater following real acupuncture” than with sham acupuncture.
Laser Acupuncture
Researchers concluded that laser acupuncture “can modulate physiological and neurovegetative parameters after stimulating the Baihui (DU20) acupuncture point” and that there was a “clear on/off-effect when the laser was activated/deactivated.”
Muscle Building
Acupuncture builds and preserves muscle mass. The research measured that acupuncture “recovered the skeletal muscle mass” and “ameliorated skeletal muscle atrophy by reducing mRNA expressions of the E3 ubiquitin ligases atrogin-1 and MuRF1.” Acupuncture also “increased the mRNA expressions of Akt1 and TRPV4.”
Pain Relief
Researchers from the University of Rochester Medical Center in New York stated, “acupuncture releases a natural pain-relieving molecule into the body…. Adenosine is a key to reducing pain during acupuncture treatment.”

IVF Relaxation Induced By Acupuncture – New Research

New research concludes that acupuncture reduces anxiety in women undergoing IVF (in vitro fertilization). A randomized-controlled study of 43 women undergoing IVF measured changes in anxiety levels. A total of four acupuncture treatments over a period of four weeks at a rate of once per week were administered. The acupuncture group received acupuncture at acupoints Yintang, HT7 (Shenmen), PC6 (Neiguan), CV17 (Shanzhong) and DU20 (Baihui). The control group received needle stimulation at non-acupuncture points near the areas of the true acupuncture points (sham acupuncture). The true acupuncture group showed a significant reduction in anxiety while the sham acupuncture group did not. The researchers concluded that acupuncture reduces anxiety and psychological strain for women undergoing IVF.
Acupuncture CEUs OnlineAcupuncture for IVFThis research focuses on the integration of acupuncture with modern medical practices and represents a trend in modern investigations. In another related recent study, research demonstrates higher ovulation and pregnancy rates for women receiving acupuncture combined with clomiphene (Clomid) compared with women receiving only clomiphene. An additional four recent studies focused on the ability of acupuncture to improve fertility treatment outcomes. An investigation of 5,807 women concludes that acupuncture improves clinical pregnancy rates and live birth rates for women receiving IVF. A study published in the American Journal of Reproductive Immunology shows that use of acupoints ST36 and SP6 prevents egg implantation failure. In a study of 309 women, electroacupuncture “significantly improved the clinical outcome of ET (embryo transfer).” Looking at basic science, researchers concluded that, “Acupuncture could improve the poor receptive state of (the) endometrium due to mifepristone by promoting Th2 cytokines secretion and inhibiting Th1 cytokines to improve blastocyst implantation.”
Point Functions
A classical acupuncture point selection, the acupoints chosen for the study have been used for anxiety reduction for over a thousand years. Yintang is renown for its stress relieving effects. HT7 (Spirit Gate) is a Shu-Stream, Yuan-Source and Earth point of the Heart channel. It is classically indicated for calming the spirit and regulating the Heart. PC6 is a Luo-Connecting point of the Pericardium channel and the Confluent point of the Yin Linking vessel. PC6 regulates the Heart, calms the spirit, harmonizes the Stomach and regulates the chest Qi. PC6 regulates the Stomach Qi and is often used to relieve nausea and vomiting. CV17 is the Front-Mu point of the Pericardium, a Meeting point of Qi, a Sea of Qi point and a meeting point with the Spleen, Kidney, Triple Burner and Small Intestine channels. CV17 regulates the Qi, opens and benefits the chest, promotes lactation and is used to benefit both breathing and relaxation. DU20 is a Sea of Marrow point and is also the meeting point of the DU channel with the UB, GB, Triple Burner and Liver channels. DU20 calms the spirit, benefits the head and brain, and subdues wind disorders such as headaches, dizziness and hypertension.
Standards
Together, these points have a synergistic ability to induce relaxation with effects that are often immediate and lasting. Variations of this point combination are common for the treatment of hypertension, insomnia, panic attacks, PTSD (post-traumatic stress syndrome) and depression. As a result, use of this point selection in this study represents a common standard for the treatment of anxiety as recommended by many Chinese medicine textbooks and classical literature.

Acupuncture Lowers Cholesterol & Triglycerides – New Research

New research concludes that acupuncture lowers both cholesterol and triglycerides. Researchers applied electroacupuncture to acupoint ST40 (Fenglong, Abundant Bulge). ST40 is located on the lower leg, halfway between the tibio-femoral joint line and the lateral Acupuncture CEUs OnlineAcupuncture at ST40malleolus at a distance of two finger breadths lateral to the anterior crest of the tibia. According to traditional Chinese medicine principles, this is a Luo-Connecting point of the Stomach channel that transforms phlegm and dampness, alleviates coughing, invigorates the channel to reduce pain, and clears phlegm from the Heart and Lungs.
The research, conducted on laboratory mice, measured biochemical responses to electroacupuncture at acupoint ST40 to map the mechanisms by which acupuncture reduces hyperlipidemia. The study discovered that electroacupuncture induces expression of nNOS and Mt1. NNOS is an enzyme that mediates nitric oxide signaling, which plays an important role in cellular signaling, vascular tone and blood pressure, insulin secretion, airway tone, angiogenesis and peristalsis. Mt1 plays an important role in the protection against oxidative stress. Based on these findings, the researchers conclude that electroacupuncture and its affect on nitric oxide signaling transduction is physiologically related to its cholesterol and triglyceride lowering effects.

Acupuncture for Spinal Cord Recovery– New Paralysis Research

Breakthrough research has discovered that implanted electro-acupuncture combined with bone marrow cell transplantation increases success rates in the healing of spinal cord injuries. Transplantation of bone marrow derived stromal cells into injured spinal cords helps in the restoration of motor functionality. However, survival Acupuncture CEUs OnlineIntegrated Acupuncturerates for transplanted cells is low thereby limiting the therapeutic value of the procedure. Researchers combined implanted electro-acupuncture with the cell transplantation procedure and concluded that electro-acupuncture “induced a significantly higher functional improvement in locomotor functions” than cell transplantation only. Electro-acupuncture also “significantly increased the number of surviving BMSCs (bone marrow derived mesenchymal stromal cells) compared to the BMSCs alone group.” The researchers concluded that “our experiment showed that the approach of coupling iEA (implanted electro-acupuncture) electric stimulation and BMSCs transplantation remarkably promotes functional improvements in animals with spinal cord injury and holds promising potential to treat spinal cord injury in humans.”
New successes with electrochemical approaches to spinal cord recovery procedures is not isolated. Recently, researchers combined electrical stimulation to the motor area of the brain and the spinal cord below the area of the injury. In addition, drugs were infused into the region of the wounded area to promote healing. The results were dramatic. Paralyzed rats were able to walk and run after severe spinal cord injuries. This research followed last year’s revelation, reported in the Lancet, that a 23 year old paraplegic man regained the ability to stand and walk using a functional electrical stimulation (FES) device.

Acupuncture Ups Blood Iron - New Research

New scientific evidence shows that acupuncture has the ability to benefit iron levels in the blood. A new study concludes that acupuncture upregulates serum ferritin and decreases TIBC (total iron Acupuncture CEUs OnlineAcupuncturebinding capacity). Ferritin is an intracellular protein that stores, releases and transports blood iron. TIBC is a lab test that measures the body’s ability to bind iron with transferrin, iron-binding blood plasma glycoproteins. TIBC is high in patients with iron deficiency anemia because the liver produces increased levels of transferrin to maximize use of remaining iron stores.
In a randomized-controlled trial, researches applied acupuncture to sixty white rabbits at acupuncture point ST36 (Zusanli, Leg Three Measures). The rabbits underwent food restriction and blood draws to simulate a blood deficiency condition that lowered serum ferritin and raised TIBC. Acupuncture was administered every other day for a total of 10 times. Serum ferritin and TIBC were measured using radioimmunoassay. Both on day 17 of the study and during a follow-up exam 32 days after completion of the study, the rabbits receiving acupuncture showed significantly higher levels of serum ferritin and lower TIBC than the control group.

Acupuncture Relieves Foot Drop From Stroke – New Research

New research concludes that acupuncture improves motor function for patients with foot drop caused by a stroke. Foot drop is movement impairment of the Acupuncture CEUs OnlineAcupuncture after Strokeankle, foot and toes that causes dropping of the forefoot. Researchers measured two approaches to acupuncture therapy for the treatment of drop foot. One of the techniques yielded superior clinical results yet both approaches showed significant clinical improvements.
Group A received acupuncture at acupuncture points SP6 (Sanyinjiao) and KI3 (Taixi) with application of the reducing needling technique at each acupoint. Tonification technique was applied to acupuncture points ST41 (Jiexi), UB62 (Shenmai) and GB34 (Yanglingquan). Group B received acupuncture at ST36 (Zusanli), SP6 (Sanyinjiao), GB39 (Xuanzhong) and several other acupuncture points used in rehabilitation treatments. Acupuncture was administered in a series of three sessions for both groups. Each session was comprised of 10 acupuncture treatments at a rate of once per day for a grand total of 30 acupuncture treatments. Group A demonstrated greater clinical improvements in the symptomatic relief of foot drop although patients in group B also showed significant improvement.

Acupuncture Reduces GERD – Univ. of Arizona Reports

A recent publication in the prestigious Journal of Gastroenterology and Hepatology cites the effectiveness of acupuncture for the treatment of gastroesophageal reflux disease (GERD). Acupuncture was shown to be more effective in reducing regurgitation and heartburn than doubling medication Acupuncture CEUs OnlineAcupuncture & GERDlevels for patients suffering from cases of refractory GERD. Dr. Ronnie Fass, MD of the University of Arizona in Tuscon reported that refractory GERD affects up to approximately one-third of patients who take PPIs (proton pump inhibitors). PPIs are pharmaceuticals that inhibit gastric acid production and include brand names such as Prilosec, Lomac, Prevacid, Nexium, and Protonix. Regarding the acupuncture research cited in the publication, Dr. Fass notes that, “This is the first study to suggest that alternative approaches for treating visceral pain may have a role in GERD patients with persistent heartburn despite PPI therapy.” Dr. Fass reported that for the approximately one-third of patients taking PPIs who continue to suffer from GERD, “When compared to doubling the PPI dose (standard of care), adding acupuncture was significantly better in controlling regurgitation and daytime as well as night-time heartburn.”

Acupuncture Trumps Ibuprofen for Shingles Pain – New Research

New research concludes that acupuncture combined with moxibustion successfully alleviates herpes zoster neuralgia, nerve pain due to shingles. A total Acupuncture CEUs OnlineAcupuncture for Shinglesof 37 cases were divided into two groups. Group 1, the medication group of 19 cases, received ibuprofen, vitamin B1 and vitamin E. Group 2, the treatment group of 18 cases, received acupuncture and herbal moxa roll heat stimulation. The herbal moxa roll consisted of corydalis tuber (Yan Hu Suo), astragali radix (Huang Qi), myrrh (Mo Yao) and other related herbal ingredients. Moxibustion was applied once a day for 7 days to Jiaji (EX-B-2) and Ahshi acupuncture points until local skin flushing was obtained. Acupuncture was applied to the same acupoints, Ahshi and Jiaji points, at a rate of once per day for 7 days. Acupuncture technique was applied using electroacupuncture at 100 Hz for 10 minutes followed by 2 Hz stimulation for an additional 30 minutes.
Following the 7 day session, one patient in the medication group was diagnosed as cured while 5 patients in the acupuncture combined with moxibustion group were diagnosed as cured. Significant improvement was diagnosed in 13 patients in the medication group and 12 patients in the acupuncture combined with moxibustion group. No progress was reported in 5 patients in the medication group while only one patient in the acupuncture-moxibustion group did not respond to therapy. The researchers discovered that the therapeutic effect achieved in the acupuncture with moxibustion group “was significantly superior to that of the medication group.” The researchers concluded that electroacupuncture with moxibustion “is effective in relieving neuralgia in HZ (herpes zoster) patients.”

Acupuncture Protects the Heart - New UCLA Research

Researchers from the University of California, Los Angeles (UCLA) conclude that acupuncture protects the heart. Electroacupuncture applied to acupuncture points P6 and P5 in anesthetized rabbits with coronary artery occlusion resulted in less ventricular arrhythmias. Electroacupuncture also decreased heart infarct size, meaning, electroacupuncture protected the heart from tissue death due to obstruction of blood and oxygen supply. The researchers also showed that electroacupuncture stimulation caused a decrease in left ventricle dysfunction. Furthermore, a decrease in harmful ST segment elevation was observed as a result of electroacupuncture at P5 and P6. A raised ST segment is measured by an EKG, electrocardiogram, and may indicate a myocardial infarction.
The Study
Acupuncture CEUs OnlineAcupuncture for the HeartIn a detailed scientific investigation published in the American Journal of Physiology Heart and Circulatory Physiology, researchers compared a non-treatment group, an electroacupuncture group, a sham acupuncture group (acupuncture at non-acupuncture points), and two additional experimental electroacupuncture groups. The two experimental electroacupuncture groups combined acupuncture with chemical blocking agents specifically designed to block the regulation of the cardiac nervous system, opioid receptors and PKC pathways. PKC is a kinase enzyme that modifies other proteins and functions in signal transduction of extracellular stimuli including hormones and growth factors. Electroacupuncture did not induce cardioprotective effects when these blocking agents were used. As a result, the researchers conclude that electroacupuncture protects the heart through regulation of the cardiac nervous system, opioid receptors and PKC pathways. The group using only electroacupuncture, without interference from chemical blocking agents, showed the cardiac improvements whereas all of the other study groups did not.
About The AcuPoints
Acupuncture points P5 (Jianshi) and P6 (Neiguan) are located on the forearm approximately 2 to 3 inches proximal to the anterior portion of the wrist. P5 regulates the Stomach and menstruation and calms the Heart. It is traditionally used for heart pain, palpitations and emotional upset. It is also beneficial in the treatment of irregular menstruation, leukorrhea, and excessive clotting of the menstrual flow. P6 benefits the Stomach, relieves nausea, regulates the Heart and calms the spirit. It is used for the treatment of heart pain, palpitations, heart rate dysfunction, emotional disturbances, vomiting and insomnia. Traditionally, P5 is referred to as a Jing-River and Metal point of the Pericardium channel. P6 is classified as a Luo-Connecting point of the Pericardium channel and is the Confluent point of the Yin linking vessel.

Acupuncture Pain Relief Related To Metal Level - New Research

New research concludes that the pain relieving effects created by electricity applied to acupuncture needles (electroacupuncture) is dependent Acupuncture CEUs OnlineAcupuncture Needleson the subdermal depths at which electricity is emitted from the acupuncture needle. Researchers measured the analgesic effects of five different types of acupuncture needles that were inserted to identical depths. However, each of the five needles had the metal exposed to the skin at different levels along the shaft.
The group 1 needle was completely uncoated and the electricity passed through the entire length of the needle. All of the other needles were coated with an insulated coating and the metal was exposed 0.2mm in length, circumferentially, at varying depths per each type of needle. The group 2 acupuncture needle had the insulated coating peeled off at the tip only. The group 3 acupuncture needle had the insulated coating peeled off at 3mm from the tip. The group 4 acupuncture needle had the insulating material removed at 5mm from the tip, and the group 5 needle had the insulated material removed from the tip and at the 5mm mark. The illustration shows the needle configurations.
The needles were inserted into acuppoints ST36 (Zusanli) and SP9 (Sanyinjiao) on 96 laboratory rats that were divided into the five needle groups. All needles were inserted at a 45 degree angle.  The rat tail-flick test was used to determine if analgesia was achieved. Once tabulated, the results showed that the group 1 and group 5 needle groups experienced significantly greater analgesia. Group 1 had the uncoated needle and group 5 had the needle type that was exposed at both the tip and at the 5mm mark. The other three groups had metal exposure at only one area and did not achieve the same level of analgesia. As a result, the researchers conclude that “the efficacy of the EA (electroacupuncture) stimulation depends on the spatial distribution of the current density under the needling surface rather than only the acupoint or the depth of needling.”

Acupuncture IVF Fertility Discovery - New Research

Researchers conclude that acupuncture improves both the pregnancy and live birth rates of women receiving in vitro fertilization and embryo transplantation (IVF-ET). During the investigation, researchers uncovered a biochemical mechanism by which acupuncture Acupuncture CEUs OnlineAcupuncture for IVFenhances fertility. In addition, the researchers compared successful IVF-ET rates with Chinese medicine differential diagnoses and made an interesting discovery.
Biochemical Discovery
The researchers found that electroacupuncture increases blood levels of HLA-G (human leukocyte antigen) “and the level of HLA-G secreted in embryos for the patients in the process of IVF-ET.” Presence of the HLA-G protein is predictive of higher pregnancy and live birth rates according to modern research conducted at the Department of Obstetrics and Gynecology, Sunnybrook and Women's College Health Sciences Centre, Toronto, Ontario, Canada.
Chinese Medicine Diagnostics
The researchers compared the Chinese medicine differential diagnostics for the women in the study. There were 82 kidney deficiency, 74 liver qi stagnation and 54 phlegm-dampness cases. The HLA-G levels were significantly higher during embryo transplantation as a result of electroacupuncture for the kidney deficiency and liver qi stagnation groups. This corresponded to differences in the “high-quality embryo rate” with the kidney deficiency group having a 73 percent yield, the liver qi stagnation group having a 70 percent yield and the phlegm dampness group having a 54 percent high-quality yield. Of interest, all three groups had similar improvements in fertilization and pregnancy rates following the application of electroacupuncture. The researchers concluded that, due to electroacupuncture, “the pregnancy outcome and the pregnancy rate are improved.”

Acupuncture For Depression Enhances Prozac - New Research

New research demonstrates that acupuncture is effective in relieving depression and increases the therapeutic effect of fluoxetine (Prozac, Sarafem, Fontex). Researchers employed a single-blind, randomized, sham-acupuncture controlled study to determine if a type of electroacupuncture called DCEAS (dense cranial electroacupuncture stimulation) “could enhance the antidepressant efficacy in the early phase of selective serotonin reuptake inhibitor (SSRI) treatment of major depressive disorder (MDD).”
Acupuncture CEUs & DepressionAcupuncture for DepressionSubjects suffering from depression received 9 electroacupuncture treatments combined with the oral administration of the SSRI fluoxetine. The results were compared with subjects receiving a non-invasive simulation of electroacupuncture stimulation (sham-acupuncture) plus fluoxetine.  The results were tabulated and the researchers concluded that electroacupuncture stimulation increased the clinical effectiveness of fluoxetine. They noted that electroacupuncture “is a safe and effective intervention that augments the antidepressant efficacy. It can be considered as an additional therapy in the early phase of SSRI treatment of depressed patients.”
The authors initiated this investigation citing numerous studies and recent meta-analyses demonstrating that acupuncture “is efficacious for various types of depressive disorders.” Citing the research, the investigators note that electroacupuncture’s rapid effects in the treatment of major depressive disorder (MDD) are due to the “direct modulation of multiple central neurochemical systems, especially the brainstem adrenalinergic (NA), serotonergic (5-HT) neuronal and hypothalamic neuroendocrine systems….” Consequently, the investigators chose dense cranial electroacupuncture (DCEAS) because it efficiently modulates these systems through stimulation of the trigeminal nerve. In addition, the investigators note that this style of acupuncture has been proven effective in the treatment of “refractory obsessive-compulsive disorder (OCD), major depressive disorder (MDD), post-stroke depression, and MDD-associated residual insomnia.” Fluoxetine was chosen as the study’s medication of choice because it is a widely prescribed SSRI used for the treatment of major depression.
The acupuncture group received 9 electroacupuncture treatments at a rate of 3 per week concurrent with fluoxetine treatment. The acupuncture points used in the study were: Baihui (DU20). Yintang (EX-HN3), Sishencong (EX-HN1), Toulinqi (GB15), Shuaigu (GB8), Taiyang (EX-HN5), Touwei (ST8). Needles were inserted obliquely or horizontally to the surface at a depth of 10-30mm. Electroacupuncture was set to a continuous wave at 9V and 2Hz for 30 minutes. Amplitude was adjusted so that the electrical stimulation was perceptible and comfortable. The patients and the raters did not know if the needles were actually inserted or if they were sham-insertions that merely simulated the acupuncture experience. A total of 70 patients were included in the data analysis.
The researchers note that electroacupuncture produces a “rapid effect in alleviating depressive symptoms in both clinician-rated (HAMD-17) and self-rated (SDS) measures of depression.” The investigators conclude that the study demonstrates that electroacupuncture is effective in augmenting the antidepressant effect of fluoxetine for the treatment of moderate and severe major depressive disorder.

Acupuncture Halts Cancer Related Hiccups - New Research

New research concludes that acupuncture effectively relieves hiccups for patients with late-stage cancer. Diaphramatic muscle spasms, intractable hiccups, occur in late-stage cancer patients. This is of great Acupuncture CEUs OnlineAcupuncture Descends Qiconcern because it is often difficult to control hiccups with medications and the hiccups interfere with the diet and sleep. A total of 30 patients were included in the investigation. 10 patients improved markedly, 18 patients demonstrated improvement and 2 patients did not respond to acupuncture therapy. Combined, the total effective rate is over 93 percent.
Chinese Medicine
According to Chinese medicine principles, a healthy stomach descends the Qi energy. Anatomically, the stomach has an important role in moving food downwards. When the body is exhausted and the stomach is weakened, the normal physiological function of the stomach to descend Qi is impaired and consequently there is rebellious Qi. This is the uprising (energetically) of stomach Qi and is manifest in hiccups, nausea, acid reflux and vomiting. The researchers chose P6, an acupuncture point that is widely used to descend stomach Qi for cases of hiccups, nausea and vomiting. The other two points have similar roles. ST36 helps to strengthen the stomach Qi and ST44 is widely used to quell an inflammatory process known as “stomach heat.”
Acupuncture Points
The researchers combined electroacupuncture, cupping and auricular acupuncture point stimulation. Electroacupuncture was applied to acupoints P6 (Neiguan), ST36 (Zusanli), and ST44 (Neiting). The acupuncture needles (0.23mm X 40mm) were stimulated manually until the arrival of the de qi sensation and then electroacupuncture was applied for 1 hour. Cupping was applied to CV17 (Danzhong) and CV12 (Zhongwan). Both electroacupuncture and cupping were applied once per day. Following the needling procedure, ear seeds made of Wang Bu Liu Xing (vaccaria seeds) were applied with adhesive to the auricular points Liver, Stomach, Heart and Subcortex. Patients were given instructions to apply stimulation to the points by pressing on the ear seeds a minimum of 3 times per day for a minimum period of 5 minutes. The ear seeds were replaced every two days. On the weekends, no ear seeds were maintained. The researchers conclude that the acupuncture protocol “is an effective method to relieve hiccups in late-stage cancer.”

Friday, June 15, 2012

Synopsis of Scalp Acupuncture


THE NATURE OF SCALP ACUPUNCTURE
Scalp acupuncture is one of several specialized acupuncture techniques with a specific body location, taking its place alongside ear, nose, hand, foot, and wrist/ankle acupuncture.  The more general acupuncture therapy is often called body acupuncture. 
Although the scalp has numerous traditionally-identified acupuncture points along several of the major meridians (notably the stomach, bladder, gallbladder, triple burner, and governing vessel), modern scalp acupuncture differs from traditional acupuncture therapy.  There are three basic features of scalp acupuncture that differentiate it from body acupuncture:
1.      Treatment zones have been mapped onto the scalp that are associated with body functions and broad body regions. The zones include a few standard acupuncture points, but the treatment principle for point selection is usually not based on the traditional indication for the point or associated meridian.  In general, within a defined zone, the forward part of the zone (nearer the face) is used to treat the upper body, while the rear portion of the zone is used to treat the lower body.  Functional zones, such as sensory, memory, and motor, are usually located at the back and sides of the scalp.
2.      In scalp acupuncture, the needles are to be inserted within a thin layer of loose tissue beneath the scalp surface, at a low angle of about 15–30 degrees, involving an insertion distance of about 1 cun [the cun is a variable unit of measure based on body size; about one inch for an adult].  Standard acupuncture of scalp points normally involves subcutaneous insertion up to a depth 1/2 cun or less (about 0.3–0.5 inches for an adult) at a high angle of 60–90 degrees. 
3.      For scalp acupuncture, the needles are to be subjected to rapid stimulation, which may be carried out in a variety of ways, including pulling/thrusting, twirling, and electro-stimulation.  Standard acupuncture applied to scalp points usually involves less rapid stimulation or moxibustion as the main stimulation technique. When using manual manipulation in modern scalp acupuncture, it is common to stimulate the needles for 2–3 minutes at a time, with a rest period of 5–10 minutes between stimulations. 
The fundamentals of scalp acupuncture therapy were reviewed by Lu Shoukang, of the Beijing College of Acupuncture, Moxibustion, Orthopedics, and Traumatology, in the Journal of Traditional Chinese Medicine (1).  According to this review, the technique is predominantly a small-needle therapy in which shu points in the scalp are treated.  Shu points refer to “stream” points where the qi of the internal organs is infused.  In the system of body acupuncture, there are 5 shu points (one for each element) on each of the 12 meridians (below the elbow or below the knee) plus the back shu points, which are each located in the vicinity of one of the internal organs.  According to the theory of channels and collaterals, shu points in the head can be used to treat diseases of the whole body. 
Lu claims that more than 80 diseases are currently treated by this therapeutic method, which is particularly effective in treating disorders of the central nervous system and various acute and chronic pain syndromes.  He mentions specific examples: neurasthenia, anxiety neurosis, and other psychological and psychosomatic disorders, periarthritis of the shoulders, ischialgia, pain in the back and loin, painful heels, and other pain syndromes, hemiplegia, aphasia, senile dementia, and other brain disorders.
During the 1970’s, scalp acupuncture was developed as a complete acupuncture system.  Three major contributors to the development of this system, Jiao Shunfa, Fang Yunpeng, and Tang Songyan, each proposed different diagrams and groupings of scalp acupuncture points.  For example, Jiao divided the scalp points into motor and sensory areas, Fang into writing (speech) and reading (memory) centers, and Tang into upper, middle, and lower burner areas.  Several different methods of needling were proposed.  Jiao advocated rapid twirling with penetrating and transverse needling; Fang favored the slight twirling method and oblique needling; while Tang recommended long-duration needle retention with superficial stimulation of the needles, using the lifting and thrusting method.
Thus, scalp acupuncture is not really a single system, but a multiplicity of systems still in development, with a 30-year history of practical experience.  A standard of nomenclature for acupuncture points has been developed (adopted in 1984 and reconfirmed in 1989), indicating 14 therapeutic lines or zones based on a combination of the thoughts of the different schools of scalp acupuncture.  However, it is often necessary to carefully review the zones relied upon by an individual practitioner, as few have adopted the unified pattern.
As Lu states in his article, Professor Zhu Mingqing (who had been associate professor at Lu’s department in Beijing before emigrating to the U.S.) has developed a popular version of scalp acupuncture.  “In recent years, Zhu’s scalp acupuncture has been a craze in Japan, America, and China.  As a school of scalp acupuncture therapy, Zhu’s method is actually derived from the standard scheme [adopted in China] and based on the clinical experience of Zhu Mingqing.  In Zhu’s scalp acupuncture, 8 therapeutic zones are used [actually, 9 zones], and the manipulation is characterized by forceful, small-amplitude lifting and thrusting of the needle, associated with massage [of the body part to be affected] and physical and breathing exercises.  In fact, the therapeutic zones in Zhu’s scalp acupuncture are determined on the basis of the standard scheme.” 
Dr. Zhu’s father was an acupuncturist who worked on scalp acupuncture, and Zhu has been working as an acupuncturist since graduating from the College of Chinese Medicine in Shanghai in 1964.  He served as assistant director of the Scalp Points Research Group of the Chinese Acupuncture Association from 1987 to 1989.  Since coming to the U.S., he has worked closely with Dr. Eva Munwu Chau, former president of the California Acupuncture Association.  In 1991, Zhu established the Chinese Scalp Acupuncture Center of the U.S.A. in San Francisco, and, in 1992, he published an English-language book on his methods: Zhu’s Scalp Acupuncture (2), now out of print.  He currently provides treatments for several neurological disorders at Zhu's Acupuncture Medical & Neurology Center, in San Jose, California (see Appendix 2 for more on Zhu’s experiences in the U.S.). 
Dr. Zhu traces the origins of modern scalp acupuncture to the work of Huang Xuelong, who in 1935 introduced the concept that there is a relationship between the scalp and the cerebral cortex.  Several acupuncturists pursued this line, seeking points and zones on the scalp that would treat diseases of the brain.  Initial results of clinical work indicated that acupuncture applied to the scalp had good effect on diseases that were associated with cerebral damage, such as stroke.  Its applications were then extended to virtually all other diseases, but a focus on nervous system disorders is still dominant.  Other physicians in China trace the acceptance of scalp acupuncture as a new system to the development of ear acupuncture, which is also thought to be especially useful for neurological disorders due to the location of needling at the head.
ZHU’S SCALP ACUPUNCTURE
According to Dr. Zhu, Baihui (GV-20) is the basis for all of the scalp points.  Quoting from the Ling Shu: “The brain is the sea of marrow.  Its upper part lies beneath the scalp, at the vertex, at point Baihui.”  The point’s Chinese name indicates that it is the great meeting place (literally: hundred meetings). Traditionally, this point is treated to stabilize the ascending yang; it is also needled in order to clear the senses and calm the spirit. 
The Governing Vessel enters the brain at point Fengfu (GV-16).  The external pathway of the Governing Vessel is used to divide the left and right sides of the scalp. The left side governs qi and the right side governs blood.  Needling of the left side has a greater impact on disorders of the left side of the head and neck, but of the right side of the body below the neck, and conversely.
In Zhu’s system of acupuncture, there are three main zones (designated the Eding zone, Dingzhen zone and Dingnie zone) subdivided into a total of 11 portions, and three secondary zones, each divided into two portions (designated Epang 1, Epang 2, front zone of Dingjie, back zone of Dingjie, Niehou and Nieqian). The zone names are simply based on anatomical descriptions.  Following is a review of the primary scalp acupuncture zones (See Appendix 1 for a picture of the zones).
Eding Zone
Ding refers to the top of the head, and E (pronounced “uh”) refers to the forehead.  The Eding zone runs from the forehead to the top of the head.  This is a zone that runs along the governing channel, covering a narrow band from a point 1/2 cun in front of GV-24 (at the forehead/scalp border) back to GV-20.  The width is 1 cun and the length is 5 cun. The Eding zone governs the yin side (front) of the body, running from the perineum (GV-20 area of needling) to the head (GV-24 area of needling).  The zone is divided into four regions.
Eding 1 is the anterior quarter of the region, extending from GV-24 forward by 1/2 cun. This region is used to treat the whole head and neck region.  The effects of treatment in this region include calming the spirit, opening the orifices, arousing the mind, and brightening the eyes. To treat, insert the needle along the side of the zone that corresponds with the side of the head or neck that is affected.  That is, although treatment usually includes one needle in the center of the zone (along the GV line), if the problem is on the right side of the head or throat, place the needle on the right side of the zone.  For example, treating blurred vision in the right eye, place one needle in the right side of the Eding 1 zone or insert the needle at the center of the zone and direct it to the right side of the zone.  The direction of needling is usually towards the face.
Eding 2 is the second quarter of the zone, extending from GV-24 to GV-22. This region is primarily used to treat disorders of the chest region. The functions include opening the chest and regulating qi, opening the lungs, stopping wheezing, and calming the spirit.  If the problem is on one side of the body, needle the side of the zone on the opposite side (contralateral).
Eding 3 is the third quarter of the zone, extending from GV-22 to GV-21. This region is primarily used to treat disorders of the middle burner (including treatment of acute appendicitis). The functions include stopping vomiting and diarrhea, regulating the liver qi, and regulating the gallbladder. To treat, use the contralateral side.
Eding 4 is the last quarter of the zone, extending from GV-21 to GV-20. This region is used to treat the lower burner and the lower limbs. The functions include regulating the menses, strengthening the kidneys and promoting urination. Needle on the contralateral side; if the disorder is central, as in bladder dysfunction, needle the central line of the zone or both sides.  The direction of needling is usually towards the back of the head.
As described above, Zhu follows the principal that if the disorder affects the left or right side of the body, then treatment that is intended to affect the head or neck is done on the same side of the zone as the side of the disorder (ipsilateral), but if it is below the neck, then the needle is placed on the opposite side of the zone.  This approach has been followed by many scalp acupuncture specialists in China.  However, a few researchers claim that clinical evidence does not support the need to treat one side or the other; rather, one can alternate sides on subsequent days.  At this time, there is probably insufficient data to demonstrate that one or the other approach is significantly better.  Alternate side needling might be better tolerated by the patient when daily needling is used.  For those following Zhu’s technique, treating one side according to location of symptoms would be consistent with his extensive clinical experience.
Dingzhen Zone
Zhen (pronounced “jun”) refers to pillow, and indicates the back of the head.  The Dingzhen zone runs from the top of the head to the back of the head, between GV-20 and GV-17. The zone is 1 cun wide. It governs the spine, the yang aspect of the body (back). It can be divided into 4 regions, equally spaced from each other. This region is mainly used for pain.
Dingzhen 1 (starting at GV-20) governs the back of the head and the neck.
Dingzhen 2 governs the vertebrae C-7 (seventh cervical, base of the neck) through T-10 (10th thoracic).
Dingzhen 3 governs the vertebrae T-10 through L-5 (fifth lumbar).
Dingzhen 4 (ending at GV-17) governs the sacrum and coccyx.  Needling here is painful, so it is rarely used.
The Eding and Dingzhen zones together form a central line from the front to the back of the scalp.  In mapping the zones to the body structure, this line represents a continuum from head to abdominal base repeated twice, first covering the front of the body (the more frontal points) and then the back of the body.  The meeting point of the two zones, GV-20, can be used to treat the entire body, depending on the aim of the needle.
Dingnie Zone
Nie (pronounced “nyeh”) refers to the temple.  The Dingnie zone runs from the center top of the head to the temple, at an angle (aiming to the cheekbones).  It is located on a line from GV-21 to 1/2 cun anterior to ST-8. The zone is 1 cun wide. It can be divided into 3 equal parts, and each part is used as a representation of a body region that can be treated within the zone.
Dingnie 1 governs the lower limbs.  The homunculus for this zone looks like a person is kneeling with their foot and thigh on top of each other (near GV-21), and their knees pointing towards ST-8.  This zone does not include the hip joint. 
Dingnie 2 governs the upper limbs.  The homunculus for this zone like a person with their elbows bent.  The elbow zone is near the region between Dingnie 1 and 2. The upper arm (not including the shoulder) and wrist are mapped near the intersection between Dingnie 2 and 3.
Dingnie 3 (near ST-8) governs the head.  It covers motor-sensory problems. This zone is rarely used as it can be painful to needle; Eding 1 is usually used instead.
Mapping from the frontal hairline back, the top of the body is forward.  Also, the sensory zone is toward the forward part of the Dingnie zone, while the motor zone is toward the back of the Dingnie zone.  Needling of this zone may include insertion from GV-21 towards ST-8 or in the reverse direction.
Epang Zone
Pang (pronounced “pong”) means along the side.  The Epang zone is a series of short segments along the border of the forehead/scalp on either side of the central line.  This zone is actually comprised of short and narrow segments running from the top of the forehead into the hair zone.
Epang 1 is used to treat acute diseases of the middle burner. It is located 1/2 cun on either side of GB-15. The zone is 1/2 cun wide.
Epang 2 is used to treat acute diseases of the lower burner. It is located halfway between GB-13 and ST-8.  The zone is 1 cun long and 1/2 cun wide.
This mapping of the body runs from the center line (GV, the Eding zone governing head and throat) to the side, progressing from head to middle warmer to lower warmer.
Dingjie Zone
Jie (pronounced “jeah”) refers to being closely bound to something: this is a zone adjacent to GV-20.  Dingjie has a front zone—Dingjieqian—and a back zone—DingjiehouQian (pronounced “chian”) means forward, and hou (pronounced “how”) means back.  The Dingjie zone is a set of four short segments arrayed from the top of the head to the front and back sides of the head.  These are short lines radiating forward and back to the sides from GV-20, the meeting spot between the end of the Eding zone (corresponding to the genital area) and the beginning of the Dingzhen zone (corresponding to the head and neck).  The front Dingjie zone treats an area of the body just above that treated by the end of the Eding zone, and the back Dingjie zone treats an area just below that treated by the beginning of the Dingzhen zone.
Front Zone of Dingjie: This zone is located on a line from GV-20 to BL-7. This area is used to treat the hips and inguinal area.
Back Zone of Dingjie: This zone is located on a line from GV-20 to BL-8. It is used to treat the area above the scapula, the upper trapezius region.
Nieqian and Niehou Zones
Nie (pronounced “nyeah”) refers to the temple.  The Nieqian (meaning forward temple) zone is near the temple, above and to the front of the sideburn, while the Niehou (meaning back temple) zone is set back from the temple (over the top of the ear).  The zones at the sides of the head are rarely used because the needling tends to be painful. 
Nieqian Zone: This zone is located on a line from GB-4 to GB-6. It is used to treat shaoyang disorders (those that are deemed half-inside and half-external in nature, and those affecting the liver/gallbladder areas, such as hypochondrium and sides of the chest), side-of-the-face problems, menstrual-related migraines.
Niehou Zone: This zone is located on a line from GB-9 to TB-20. It is mainly used to treat diseases of the ear.
MAPPING OF THE BODY WITHIN THE ZONES
The Dingnie zones, which extend at angles towards the front of the head (from GV-21 to ST-8 on either side) from the central Eding zone, overlap the central zone.  The mapping of body parts to the zones places the foot at the beginning of the Dingnie zone (at GV-21) and the head at the end of the Dingnie zone (at ST-8):  Dingnie zone #1 is used for treating the legs; Dingnie zone #2 is used for treating the arms; Dingnie zone #3 is used for treating the head.  However, because Dingnie zone #3 is more painful to needle and, because treatment of the head is adequately accomplished in the Eding zone #1; Dingnie #3 is seldom used by Dr. Zhu. 
To visualize the mapping, imagine a person squatting down with arms bent, placing the elbow on the knee, with the hand by the shoulder.  The beginning of Dingnie #1 is at the base of the foot, this overlaps with the upper thigh due to the squatting position, and then it maps upward to the knee; the zone then continues up the arm from the elbow towards the hand and shoulder, including the forearm in that same space (Dingnie #2); finally, it follows up the head (Dingnie #3).  The foot location of the Dingnie zone #1 extends all the way to the far side of the Eding zone (the Eding zone runs along the governor vessel; the zone covers 1/2 cun on either side of GV; when needling Dingnie to treat the foot, the point of the needle, threaded into the scalp, rests at the junction of the beginning of Dingnie zone #1, where it meets the far side of Eding.  Therefore, the needle enters the scalp behind the Dingnie zone.  Dingnie zone #1 does not include the hips, and Dingnie zone #2 does not include the shoulder girdle; to treat those parts of the body, Dr. Zhu relies primarily on the Dingnie zones.  Aside from the standard zones, palpation of the scalp for tender points helps Zhu to identify the specific needling sites within the selected zone.  The Eding zone is the most frequently used of the scalp zones, with the Dingnie zones being used additionally for treating affected limbs.
When treating a neurological problem that affects the extremities, the needles are directed, along a zone, towards the opposite extremity.  Thus, for example, if the left leg is affected, the needle will be directed outward along Dingnie #1 on the right side of the scalp.  Only for problems of the head and neck is the needling done on the same side of the scalp as the disorder.  For disorders that are not specific to a body location, such as hypertension or epilepsy, needling may be done on both sides of the zone.
If the disorder to be treated is associated with a degenerative disease involving a kidney deficiency syndrome (common in elderly patients and those with chronic, degenerative diseases), then Eding zone #4 is usually needled.  A typical needling pattern is: one needle in the center of the zone, and one needle on either edge of the zone, about 0.5 cun apart from the central needle; for a total of 3 parallel needles in the zone, with the central needle leading the other 2 by about 0.5 cun, producing an arrow formation; the outer 2 needles are directed towards the part of the zone that corresponds to the kidney, while the inner needle is directed toward the part of the zone corresponding to the genitals.
Dr. Zhu sometimes uses a “crossing” technique for needle positioning, mainly in treating cases of severe pain.  He selects a zone site for treatment, and inserts one needle along the zone and then inserts a second needle perpendicular to that one, going across the zone and crossing over the first needle.  As an example for right-knee pain, a needle is first directed along Dingnie #1 towards the left temple, and then a second needle is inserted across that one.  The second needle is stimulated by the draining method.  In cases of quadriplegia, another crossing technique is used. The first needle is inserted across the zone (e.g., from the left part of the zone to the right part of the zone, at about a 45 degree angle), and then a second needle, crossing over the first (e.g., from the right part of the zone to the left part of the zone).  In some cases, a series of cross-over needles are inserted along the length of a zone (this may incorporate as many as 3 pairs of needles).
THE NEEDLING TECHNIQUE
The needle size often mentioned in Chinese texts for scalp acupuncture is 26, 28, or 30 gauge, which is suitable for rapid twirling techniques.  For Zhu’s needle stimulation technique (thrust and pull method), a somewhat finer needle gauge of 32 or 34 is suitable for most cases, and the insertion length is approximately 1 cun.  A 30 mm (1.2 inch) needle with a wound head is thought to be the best.  The needle must be long enough so that it is not inserted up to the handle, but short enough that there will not be any bending during insertion and manipulation.  The angle of insertion is typically 15–25 degrees.  The patient should not feel pain, though there are some rarely used scalp points along the sides of the head, mentioned above, that typically produce pain.
The needle is inserted along the practitioner’s nail pressing the skin.  Press besides the treatment zones with the nail of the thumb and first finger of the left hand, hold the needle with the right hand, and keep the needle tip closely against the nail.  By avoiding the hair follicle, one can minimize pain during insertion. The direction of needling is usually based on the mapping of the body within the zone being treated: the needle is aimed (along the line of the zone) toward that portion of the zone most closely corresponding to the area of the body that is affected by the injury or disease.
Although the distance from the skin surface to the skull is very short, there are several tissue layers: the skin, hypodermis, galea aponeurotica and occipito-frontalis muscles, subaproneurotic space, and pericranium.  The subaproneurotic space is a loose layer of connective tissue that is ideal for penetration during scalp needling: the needle slides in smoothly and does not cause pain, yet the desired needling sensation is strong.  If the angle of needling is too shallow, the needle will penetrate the skin and muscle layers and it will be difficult to get a smooth insertion. 
Upon inserting the needles, stimulation is applied for 1–2 minutes (see below for stimulation technique).  The needles are manipulated again after intervals of 10–15 minutes, for 1–2 minutes each time, throughout the duration of the patient visit, which may be as long as 2–3 hours.  Sometimes, the interval between needle stimulation sessions is longer due to insufficient staff time when there are numerous patients, but usually within 30 minutes.
The needles should remain in the scalp for a minimum of 4 hours (except for treatment of acute symptoms, in which case, 0.5–1 hour is sufficient) and up to a maximum of 2 days.  However, for children and weak adults, the time of retention should be shorter.  Dr. Zhu generally prefers long-term needle retention of 1–2 days; this is in contrast to the method of Jiao Shunfa, who advocated removing the needles after the basic manipulations.  At Zhu’s clinic, the scalp needles are often left in place when the patient leaves, and are not removed until the next visit, which is 24–48 hours later.  At that time, new needles are inserted at different points.  If several parts of the body are affected by the illness or injury, the points selected may be rotated through a cycle aimed at treating each of the different body parts.
There are two basic needling methods for manipulating the qi, designated jinqi and chouqi, that have been elucidated by Dr. Zhu.  Both are based on ancient techniques and involve a rapid, short distance movements.  Jinqi (jin means move forward) is a tonifying, thrusting method.  “Thrust the needle quickly with violent force, but the body of the needle doesn’t move, or no more than 0.1 cun in.” Following the thrust, the needle is allowed to settle back to its original position. Chouqi (chou means to withdraw) is a sedating, reducing method.  It is based on forceful movement and a lifting motion.  “Lift the needle quickly with violent force, but the body of the needle doesn’t move, or no more than 0.1 cun out.”  Again, after the pull, the needle settles back to its original position. 
Lu Shoukang mentions in his article that he prefers using the small-amplitude, forceful lifting method, rather than the twirling method, because “it saves the operator effort and gives the patient less suffering.”  He describes his preferred method as follows: “When inserted to a certain depth (about 1 cun), the needle is forcefully lifted outwards or thrust inwards.  The direction [angle] of lifting or thrusting is the same as that of the insertion.  The outward and inward force exerted on the needle should be sudden and violent as if it is the strength from the whole body of the operator.  The lifting and thrusting amplitude should be small, no more than 1 fen [1/10 cun].  After lifting and thrusting continuously for three times, the needle body is sent back to the original place (about one cun) and significant therapeutic effects will be obtained after the maneuver is repeated for 2–3 minutes.” 
For the majority of neurological disorders, the tonification technique (jinqi) is used, with a series of rapid, very small-amplitude, in-out needle movements.  The emphasis is on the forward movement, then allow the needle to naturally pull back to the starting position.  In cases of pain syndromes, the draining method (chouqi) is used, with the same kind of rapid, limited distance movements, but with the emphasis on outward movement, then allowing the needle to settle back in to the starting position.  During the stimulations, it is important for both the practitioner and the patient to focus on the breath (this is an aspect of qigong therapy that is incorporated into the treatment).  There should be no talking during needle stimulus: all attention is on the needling and its effects.  The mental focus is on “directing the breath” to the body part that is to be affected.
Regarding repetitions of the stimulus, Zhu says: “Repeat many times until revival of qi and effect is achieved.”  He usually does not specify a manipulation duration, but rather bases the duration on observed response.  He claims that by using the small amplitude manipulation method rather than the twirling method, one has the advantages of “large amount of stimulation, saving effort, less pain sensation, and strong needling sensation,” yet the therapeutic effects are achieved quickly.  The method is also easy to master, though success may depend on the qi of the practitioner when utilizing the forceful but small amplitude manipulations.  Dr. Zhu does not rely on moxa, due to the problems associated with large amounts of smoke in the group treatment setting and lack of adequate ventilation at the Neurology Center.  He does use heat lamps to provide heat to an affected body part, when it is deemed valuable.
The affected part of the body is to be moved during needle stimulation.  If the person cannot make the movement on their own, then the patient will visualize moving the breath to the affected part and, when possible, an assistant will move the body part.  After the needle stimulation, the patient is encouraged to continue the movements.  In cases where the legs are involved, the patient walks, if possible (several patients at Zhu’s clinic would walk around the block, others might walk the length of the room).  Dr. Zhu expressed the belief that a function of scalp acupuncture is to improve or re-establish the connections from the central nervous system to the peripheral nervous system.  The sending of signals between these two parts of the nervous system during treatment is critical.  The intention of the patient to move the affected body part (or the mental practice of moving the breath to the body part) sends signals from the central nervous system to the periphery, while actual movements of the body part send signals back from the periphery back to the central system.
Before withdrawing the needles, Zhu recommends manipulating the needle again while the patient performs breathing exercises.  When it is time to remove the needles, press the skin around the point with the thumb and index finger of the left hand, rotate the needle gently and lift slowly to the subcutaneous level.  From there, the withdrawal should be rapid, and the punctured site should be pressed for a while with a dry cotton ball to avoid bleeding.
Body points are sometimes used as an adjunct to the scalp acupuncture therapy. Dr. Zhu uses relatively few body points (typically 1–3, if any), but emphasizes obtaining the qi sensation with propagation of qi sensation towards the affected part.  Examples of body points are ST-36 for lower limb weakness, or LI-11 or GB-20 for arm weakness.  If a body part affected by disease or injury involves very localized pain or spasm, Dr. Zhu might use body points primarily for local treatment (rather than somewhere else along a meridian affecting the area), and usually with deep needling.  Body points are sometimes selected because of failure to obtain the desired qi reaction when using scalp points. The body needles are also retained during the full length of the patient’s long scalp acupuncture treatment, for up to two hours, not just 20–30 minutes as is often the case with standard acupuncture therapy.
In most cases, treatment is given every day (at least 5 days per week) for 1–2 weeks, then every other day for another 1–2 weeks, followed by twice per week treatment for as long as necessary.  The frequency of treatment may be adjusted according to the severity of the condition and rate of improvement.  According to Lu, for best results in treating hemiplegia due to stroke, scalp acupuncture should initially be performed twice per day.  For other chronic conditions, daily treatment or every other day treatment is recommended for the initial therapeutic plan, to be followed-up by less frequent treatments once progress has been made.
CONCLUDING NOTES
It is evident that after 30 years, scalp acupuncture is still evolving in its techniques and applications.  In America, Dr. Zhu and his students have developed the techniques to suit the Western patients (see Appendices 2, 3, and 4).  In reviewing the Chinese literature (see Appendix 5), one can draw certain general conclusions.  Most authors suggest that utilizing scalp and body acupuncture together is a valuable method.  The recommended frequency of treatment is high, from once or twice per day to once every other day, with a course of treatment typically involving 10–12 consecutive sessions, followed by a break of 2–4 days, sometimes 5–7 days.  Needle insertion, manipulation, retention, and removal are approached with differing techniques.  An expressed concern is to minimize pain for the patient and also to make the procedure practical for the acupuncturist.  Thus, the frequently-mentioned method of rapid needle twirling may be replaced, in some cases, by other methods (including electrical stimulation) because of the potential for causing pain for the patient and fatigue and irritation for the acupuncturist.  At least one study compared the efficacy of twirling (manual and machine-aided) and electrical stimulation and the conclusion was that both were useful.  The twirling method with large needles remains a common practice in China.
In all cases, it is considered important to obtain an appropriate needling sensation (not pain); often, this is to be accomplished by utilizing needle manipulation at least two to three times in the course of a single session (for 2–3 minutes each time).  The manipulation is usually rapid, with frequency of twirling in the range of 150–300/minute or electrical stimulation reported in the range of 150–700/minute.  Total duration of needle retention in most cases is 20–45 minutes, though some patients are sent home with needles in place (as Dr. Zhu recommends), for retention of several hours up to a maximum of 2 days.
Indications for scalp acupuncture include virtually all the usual indications for body acupuncture, but the main applications are stroke, paralysis, pain, and emergency situations (Zhu has published a book regarding the latter: A Handbook for Treatment of Acute Syndromes by using Acupuncture and Moxibustion (3), which includes scalp and other acupuncture techniques).  Contraindications for scalp acupuncture include very high blood pressure (220/120), heart disease, infection, post-operative scars in the acupuncture zone, some cases of pregnancy (mainly habitual miscarriage), persons who are extremely nervous, and infants whose fontanels have not closed.
In a report from Harbin (18), several aspects of scalp acupuncture for stroke patients were commented upon, which largely match the methodology and interpretation expressed by Zhu:
1.      The needle runs in the layer of loose connective tissue between the galea and the pericranium.
2.      The response of “getting qi” is more importantly measured by observing an improvement in movement or sensation of the affected part of the body rather than a needling sensation like the one that is generated when the affected parts are directly needled.
3.      Scalp points are especially effective because they are close to the part of the body that is affected, namely the brain.
4.      Prolonged stimulation time, with rapid needling speed, gives better results.  For example, constant needle twirling [the stimulation method more often used in China] for 3 minutes gave superior results to constant twirling for half a minute.
5.      The effect of scalp needling is to stimulate the cerebral cortex; it can reverse the imposed inhibitory mechanisms on nerve function, revive cells that are not completely destroyed, and enhance the function of nerve cells that are subjected to ultra-low oxygen levels.
In general, Chinese clinical reports indicate a high degree of effectiveness; cases and situations leading to better or poorer outcome have been elucidated.  In America, there is less tendency to provide daily acupuncture, which might reduce the effectiveness.  Given the general unfamiliarity with acupuncture, there is more likelihood of patients waiting to try acupuncture as a last resort rather than a first effort, so that the chances of improvement are more limited.  The scalp acupuncture technique taught by Dr. Zhu has been used at ITM’s An Hao Natural Health Care Clinic in Portland to treat a multiple sclerosis (see Appendix 3 for protocol details), peripheral neuropathy, migraine headache, and Bell’s palsy.  Good results were attained in cases where body acupuncture had not been sufficiently effective. 
APPENDIX 1: Zone Charts

      
      
Acupuncture Zones in Zhu’s Acupuncture.

APPENDIX 1, continued: Zone Charts


Acupuncture Zones Based on Motor/Sensory, Speech/Hearing, and Other Divisions
(not used in Zhu’s acupuncture system).

Appendix 2: Dr. Zhu’s Work in America
Dr. Qingming Zhu opened his neurology clinic for scalp acupuncture therapy in Santa Cruz, California in October, 1997, after offering his services for 6 years in San Francisco.  Santa Cruz is a small beach town about 85 miles south of San Francisco that supports an acupuncture college—the Five Branches Institute. The neurology clinic shares space in the same building as the college, serving also as a training center for acupuncture students.  Another acupuncture clinic is also in the same building, staffed by several experienced Western practitioners, and provides the more standard variety of acupuncture therapy. Although Zhu has learned English, his work is aided by a translator who can speed up and clarify the communications. Still, many of his house calls are made without this help.
While Zhu’s work has gotten some favorable press, his efforts at helping those with neurological problems remains an uphill battle.  In California, medical insurance generally covers the cost of acupuncture, but insurers have repeatedly refused to pay for other medical expenses associated with Zhu’s work, such as special exercise equipment developed for those with paralysis, herbal treatments, and extended physical therapy.  The main hospital in neighboring San Jose, after initially letting him work on in-patients, has since refused to continue such permission, viewing his techniques unfavorably, despite the overwhelming support of those receiving the treatments.  Medical doctors have scoffed at his claims to be able to help quadriplegics by scalp acupuncture.
His clinic is a small facility with one main room, having a dozen chairs for patients to sit on while receiving scalp acupuncture, and a pair of curtained-off segments of the room for beds so that patients can receive acupuncture while lying down.  There is a small office, which often turns into a treatment room, and one small private treatment room off the office.  At this facility, about 20 patients visit each day, staying for 2–3 hours: after the needles are inserted, Zhu stimulates the needles from time to time.  The room becomes quite crowded as most of the patients come with helpers.  The clinic is usually open only 4–5 hours a day; much of the rest of Zhu’s long and grueling work day is spent making home visits to those who are so severely impaired that they can’t travel to the clinic.  He also teaches at the college.
His treatment technique relies almost exclusively on scalp acupuncture, sometimes using a dozen or more needles in the scalp at one time for the more severely debilitated patients.  Although the needling is sometimes painful, he has adapted the treatment so that even babies and young children accept it.  Zhu rarely prescribes herbs, but primarily relies on frequent scalp acupuncture therapy (daily or every other day).  He has a few patent remedies available at his clinic and has access to crude herbs for making decoctions, or preparing topical applications, from the college pharmacy.
Zhu treats a wide range of neurological problems, including cerebral palsy, epilepsy, injury-induced paraplegia, multiple sclerosis, and post-stroke syndrome, as well as disorders that seem to fall beyond the ability of neurologists to pin them down with a name.  The results of Zhu’s work are somewhat difficult to elucidate.  With the absence of support from the community of neurologists who could provide detailed monitoring, and the limited assistance available during patient treatment (which doesn’t permit careful documentation of the cases), the extent and nature of the responses are not well established. At Zhu’s clinic, patients report notable improvements compared to their earlier conditions.  In a few cases of quadriplegia, Dr. Zhu is using a video camera to illustrate the extent of changes in patient capabilities.  For more information on Dr. Zhu and his clinic, write: Zhu's Acupuncture Medical & Neurology Center, 100 O'Connor Drive, Suite 20, San Jose, CA 95128, or call Five Branches Institute (831-476-9424).
APPENDIX 3:  Scalp Acupuncture Protocol for Multiple Sclerosis
The following protocol was developed by Dr. Edythe Vickers, based on the teachings of Dr. Mingqing Zhu, and is being used at the Institute for Traditional Medicine.
1.      If the primary lesions are in the brain, insert needle in Eding Zone 1, needling along the GV line towards the face.  This is intended to improve vision (e.g., to relieve optic neuritis) and increase mental clarity.  If the primary lesions are in the neck, then insert the needle in Dingzhen Zone 1, which governs the neck.
2.      Insert needle from Eding Zone 3 to Eding Zone 4, needling along the GV line towards the back of the head.  This is intended to tonify the kidney/liver system that is weak in nearly all persons with multiple sclerosis.  If the patient is suffering from a bladder disorder (typically, there is inability to completely empty the bladder, and there may also be incontinence; many individuals rely on a catheter), then needle only within Eding Zone 4.  This latter treatment is the same as selected by Chen and Chen (4) for treatment of enuresis.
3.      Use two additional needles to complete the treatment.  For persons who are not highly symptomatic, the two needles may be placed parallel to the needle in Eding Zones 3 and 4, about 1/4 inch on either side of the central needle.  This will enhance the tonification of the liver/kidney system and strengthen the legs, bladder, and abdominal organs.  For persons who have weakness, tingling sensation, or other disorders affecting the arms and hands, needle instead Dingnie Zone 2, with the needle aiming towards the face (towards ST-8).  If the problem affects one side of the body, needle the opposite side of the scalp, but if it affects both sides, needle both sides of the scalp.  For persons with weakness and numbness in the legs, use Dingnie Zone 1, with the needle towards the GV-21.  For persons with aching and numbness in the shoulders, needle the Dingjie  Zone.  Again, needle either one side or both sides, as appropriate.
Use the thrusting technique (jinqi) in most cases, as this will tonify the deficiency.  The manipulation should be carried out until the patient notices a change in their condition.  When treating the arm or leg scalp zones, have the patient attempt movement of the body part while the needle is manipulated.  For bladder disorders, have the patient breathe deeply (to the lower abdomen, Dan Tian), which should focus attention on the area being treated and help to produce a warming sensation.  When treating Eding 1 (for the eyes), have the patient gently rub their palms over the eyes. 
If an effect is not noted (clarifying of vision, change in sensation or strength in affected limbs) within about 3 minutes of manipulation time, check that the needling location and needle placement are correct; if correct, it may be necessary to try the lifting method (chouqi) instead, especially if there is pain. It may also be valuable to treat body points, such as ST-36 and GB-34 for the legs and LI-4 and LI-11 for the arms.  Once a response is noted, the needle manipulation can be ceased.  Patients with leg weakness should attempt to walk for a few minutes.  After about 15 minutes (from the previous manipulation), the needles should be manipulated again.  At the end of the third manipulation, the patient will be instructed to retain the needles for a period of several hours, up to two days, and then remove the needles themselves or with the aid of someone who can assist them.  The needles used for body acupuncture are removed at the end of the in-clinic treatment session.
Appendix 4: Treatment Method at Vitality Center
Holly Gahn, L.Ac., O.M.D., has been using scalp acupuncture for several years and currently practices at Vitality Center in Lake Forest, California.  She described her basic treatment techniques as follows, indicating that there are a number of other procedures that she may utilize to complete the treatment:
Treatment Course.  On the first day, the patient is treated in the morning and in the evening; for the next nine days, the patient is treated once daily.  Then, treatment continues at the rate of three times per week until the condition has resolved or the patient has reached what appears to be the maximum level of improvement.
Point Selection.  The motor, sensory, balance, vision, and speech areas are utilized as appropriate.  For unilateral paralysis, use the contralateral side, but use bilateral treatment of the zones for bilateral paralysis.  In cases of generalized brain damage (as occurs with anoxic brain damage), Zhu's Eding zone is used predominantly, along with GV-24 and UB-3 bilaterally.  If the patient's scalp becomes sensitive to needling, as might occur with frequent needling of the same zone, it is helpful to alternate (from one treatment to the next) between the motor and sensory points and the Eding zone.
Needling Procedure.  Needles are inserted one cun obliquely into the subaproneurotic space.  Needles point downwards and are angled off towards the affected limb.  It is stimulated by small-amplitude, lift and thrust technique at rapid frequency (200 times per minute if possible).  Body needles are also inserted, using standard procedures.  Both the scalp and body acupuncture needles are retained for 20–30 minutes and stimulated every 2–3 minutes during this time. 
Neuromuscular Re-education.  Immediately after the basic needle treatment, the body needles are removed, but the scalp needles are retained.  The patient is taken through a series of exercises while the scalp needles are being stimulated simultaneously.  If the patient is comatose or otherwise unable to perform these, the practitioner (or assistant) performs the otherwise passive motions for the patient.  The patient, all the while, is encouraged to try to think about doing the exercises, to visualize it, to visually watch the movements (if possible).  Verbal encouragement is even given to those who are comatose.  As soon (in the treatment course) as the patient is able to perform the movements, they are encouraged to do so, even if the movement is slight.  Electrostimulation may be utilized (frequency is 200/minute) in place of manual stimulation.  As they become stronger, the practitioner adds resistance to each exercise (weights can be added), thus requiring the patient to apply greater strength (and, in some cases, more muscle groups) to the task.  The effort put forth by the patient is of utmost importance. 
For Comatose Patients.  Needle PC-8 and KI-1 bilaterally plus GV-26.  The needles should be stimulated strongly (manual) for 10 minutes.  Then add PC-6 and SP-6 with strong stimulation before proceeding to needle the rest of the body and scalp.
APPENDIX 5:  Commentaries and Clinical Observations from the Chinese Literature
1.  About needling techniques and duration.
For peripheral facial paralysis, Cui Yunmeng (7) suggests using a .38 mm needle and a 75 mm length.  The needle is twirled at a speed of 200 times per minute.  Needles are retained for 20–30 minutes, being twirled twice.  Needling is done in the facial motor area of the scalp, on the same side as the affected part.
For treatment of hemiplegia, Wang, et al., (6) give extensive details regarding point selection (a combination of scalp and body points).  Acupuncture is given once daily for 40 minutes, with 10 days as one treatment course, and a rest of 3 days between courses.  After insertion, the needle is twisted for 5 minutes at a speed tolerable to the patient who is advised to exercise the limbs as best he can.  Electric acupuncture is then used at a frequency of 150–200 pulses/minute for the head points and 100 pulses/minute for the body points.
Lu Shoukang (1) says that: “In scalp acupuncture there are many types of manipulation.  The common one is the rapid needle-twirling method, that is, after being inserted to the lower layer of the galea aponeurotica, the needle is tightly held by the thumb and index fingers, and rapidly twirled for about 200 times per minute.  This manipulation requires a high frequency and continuous movement and lasts 2–3 minutes each time.  Within half an hour, the manipulation should be done 2–3 times.  Owing to the fact that by this method the needle often twines the muscular fibers and causes pains, it is not well accepted by the patient.  Furthermore, the metacarpophalangeal joint of the operator fatigues easily.  For this, the finger twirling is replaced by electric twirling, in which the patient is given pulse electric stimulations with dense and loose waves and a current intensity tolerable by the patient.”
For the treatment of post-stroke syndrome, Pang Hong (9) reports the following method, based on the teachings of K.Y. Chen: “Scalp acupoints were needled with the reinforcing or the reducing method as indicated.  For reinforcement, the filiform needle was inserted at an angle of 15–30 degrees to the scalp, slowly and forcefully to beneath the aponeurosis.  Pressure was applied to the point for one minute, and the needle was quickly withdrawn after a retention of 10 minutes.  For reduction, the manipulations were similar, except that after 10 minutes of retention the needle was withdrawn slowly, when the skin formed a mount around the retreating needle.  For either reinforcement or reduction, the needling took 15 minutes, including the 10 minute period of needle retention.  Courses of treatment were 10 daily sessions, with efficacy appraised after three courses.”  He went on to comment that: “For the promotion of myodynamia and motile functions, the method of slow-rapid reinforcing-reducing was significantly better than the method of flat twisting.  The application of reinforcing and reducing manipulations would shorten the therapeutic course, promote the therapeutic efficacy, and decrease the rate of disability.  The method of slow-rapid reinforcing-reducing in scalp acupuncture had the advantages of causing less pain and inducing proper occurrence of the needling sensation; therefore, it was well received by the patients.” With regard to the selection of points, Pang Hong claims that: “For the treatment of apoplexy, the selection of acupoints on either the healthy or the affected side makes no difference in therapeutic efficacy.”  In his clinical work, he treated both sides, alternating sides from one session to the next. 
In a teaching round on apoplexy (10), Professor Guo describes his technique for scalp acupuncture: “Size 28 needles are commonly used, usually of the length of 2 cm.  First, locate the upper point of the motor area, and with the left hand fixed on it, insert the needle obliquely towards the lower point at an angle of 15 degrees with the skin surface.  Holding the needle with the right first three fingers, insert the needle quickly until it reaches the loose cellular tissue beneath the scalp.  Then turn the needle horizontally with respect to the skin surface, and push it to a depth of about 1.5 cm.  Twist and rotate the needle but never lift and thrust it.  Hold the needle between the medial surface of the terminal part of the right index finger and the palmar surface of the terminal part of the right thumb.  With repeated extensions and flexions of the interphalangeal joint of the index finger, one rotates the needle in one direction till it turns two rounds and then in the other direction for another two rounds.  One may rotate this way 200 times for one minute, repeat rotating 5–10 minutes later, and retain the needle till 30 minutes after the insertion (including the time of rotating).  With rotating of the head of the needle, the patient usually reports the feeling of local heat, numbness, and tics.  There may sometimes be radiation of such feelings to contralateral and homolateral limbs.  In general, therapeutic effects are achieved with mere appearance of local needling feeling; nevertheless, still better results will be had if the feelings radiate to the limbs.  You may produce all the needling feelings with electrical stimulation.  To do this, one inserts a 1 cun needle into the upper point of the motor area and pushes it horizontally towards the lower point, and then insert a 1.5 cun needle at the division point between the upper 1/5 and middle 2/5 [of the motor area].  With these needles connected to corresponding electrodes in the electroacupuncture apparatus, one then passes electricity, often in a frequency of 3/sec [180/minute] with a tolerable intensity for 20 minutes.”
Qu Hong and his colleagues (8) described their scalp acupuncture technique for treating pseudobulbar paralysis as follows: “A filiform needle was rapidly inserted for a depth of 1–1.5 cun in the direction of the motor/sensory area, followed by rapid twistings for 0.5–1 minute until the appearance of the needling sensation.  The needle was retained for 40 minutes, with small amplitude twistings for another 0.5–1 minute before withdrawal....Practice has shown that needling on the motor and sensory areas simultaneously, and on the affected side and the healthy side simultaneously produces better curative effects.  In light of the experience of Professor Shi Xuemin, the authors adopted deeper insertion of the needles both on the scalp and on the body. Retention of the needles enhanced vasodilation of the cerebral vessels to increase cerebral circulation more than simple twistings of the needles for the recovery of nervous functions.  The authors therefore lengthened the needle retention to 40 minutes.”
Liu Chunhui and Wang Ying (11) reported on their experience of treating acute apoplexy during a medical visit to Yemen.  For scalp acupuncture, they reported that: “The needles were twirled once every 10 minutes at a rate of 200 times per minute, followed by retaining them for 30 minutes.  The patients were asked to exercise the limb during the needle manipulation.”  The manipulation was applied every 10 minutes and acupuncture (body plus scalp) was administered each morning and afternoon for a treatment course of 12 days, with an interval of 3 days between courses (using 1–6 courses).
Wu Chengxun (12) reported on using three techniques of needle manipulation.  Manual twirling was done with a frequency of 200–500 times per minute and the twirling was performed every 3–5 minutes; a needle twirling machine was applied at a frequency of 300 times per minute and applied in the same fashion; an electroacupuncture device was used with a frequency of 500–700 waves per minute, with continuous stimulation for 10 minutes.  After the stimulations were applied, needles were retained for several minutes so that the total duration of needling was 25 minutes.  The treatment was performed daily for 12 days, and then a rest period of five to seven days was allowed before resuming another course of 12 days treatment.  With a total of 1228 cases of hemiplegia so treated, it was determined that there was no significant difference in the outcome for the three methods of stimulation.
Ji Nan and colleagues (13) used scalp and body acupuncture to treat sequelae of stroke and cerebral injury, claiming improvement in all but 3 of 128 patients, with treatments deemed markedly effective in 42.8% of the total group.  Needles were inserted, as appropriate to the condition being treated, into zones designated motor area, sensory area, vasomotor area, and speech zones I, II, and III.  For paralysis, they used the method of treating the side opposite the affected limb.  The scalp needles were connected to a therapeutic instrument which delivered “sparse and dense waves” over an interval of twenty minutes for each session.  For each session 1 or 2 scalp areas and 2–4 body points (such as ST-36, LI-10, LI-11, LI-15, GB-34, or SI-9, getting qi and then allowing 20 minutes retention) were treated.  Sessions were once daily for 10 days as a course of treatment, applying 2 courses as the standard.
Zhang Naizheng (14) described treatment of tremor artuum in 35 individuals using a combination of body points and scalp acupuncture.  Regarding the latter, he stated: “The dancing tremor controlling region was chosen; needling was done once per day, 10 days for a course of treatment, with an interval of four days between courses, lasting 4 courses.  Using a 26 or 28 gauge, 5 cm long needle, the squeeze-holding method was used for insertion; the angle of insertion was 30 degrees, and the needle was rapidly twirled with a small scope of movement, about 200 times per minute for 2 minutes, and then retained without twirling for 5 minutes; this procedure was repeated three times and then the needle was removed.”
Zhang Mingju reported (15) on treatment of 296 cases of hallucinations using scalp acupuncture.  The method used was point-through-point needling, with the needles inserted at an angle of about 15 degrees with the scalp and running from GV-19 to GV-20 (the Dingzhen 1, which affects the head); auxiliary treatment locations were needled by similar method, starting at the selected point and then needling through to the next point (examples: GB-17 to GB-16; TB-19 to TB-17).  Needles were twirled and agitated for 1–3 minutes.  When the needling sensation is felt is the best time to channel qi to the locality of the disease.  Needles were retained for 1–3 hours.  Acupuncture was performed daily, and 10 sessions constituted on therapeutic course.  After the first course, acupuncture was performed every other day, with 10 sessions constituting the second therapeutic course.  If still necessary, acupuncture was performed twice weekly, with 10 sessions constituting the third therapeutic course.  By this method, 71% were cured and 19% markedly improved.
Zhang Hong reported (16) on treatment of 76 cases of senile urinary incontinence.  Body and scalp acupuncture was used, with scalp points picked in the leg motor and sensory area (1 cm lateral to GV-20, corresponds to Eding 4) and reproduction area (Epang 2).  Electrical stimulation was adopted, with a frequency of about 200 pulses per minute, with the intensity limited to the patient's tolerance.  Needles were retained for 30 minutes.  Treatment was given 5 times per week, with 10 treatments constituting one course, with an interval of one week between courses.  After 1–2 courses, half the cases were cured, and 20 others markedly improved.
2.  About needling pain and needle sensation
Lu Shoukang observes (1): “In scalp acupuncture, the needle is usually inserted by the penetration needling along the skin.  Since the scalp is rich in nerves and blood vessels and is more painful than the limb when punctured, the needle insertion should be rapid and kept away from the hair follicles and the tip of the needle should be sharp.  After insertion, the needle body should be rapidly pushed to the lower layer of the galea aponeurotica that is the loose connective tissue to allow the needle to be manipulated freely to cause less pains.  In order to strengthen the stimulative sensations, the point-through-point method is used, that is, the needle penetrates several points at the same time.  Sometimes the method of two needles punctured to each other is used.  For instance, one needle is punctured from qianding [GV-21] to baihui [GV-20] while the other needle from baihui to qianding, both along the midline of the vertex.”
Chen Zaiwen and Chen Ling (4) described treatment of enuresis in children with scalp acupuncture.  It was mentioned that: “For scalp acupuncture, the selection of acupoints needs to be accurate and the manipulation mild to avoid unnecessary pain which might dispose the child unfavorably to acceptance of the treatment.  The author’s choice was a 30–32 gauge filiform needle, 1.5 cun in length.  It was desirable to insert the needle rapidly through the skin in a vertical direction and then the needle was bent to an angle of 30 degrees to the skin to be pushed forward, preferably under the epicranial aponeurosis.  A stronger stimulation often brought about better curative effects.”  Although the authors reported good clinic effect of scalp acupuncture for enuresis, it was said that: “Owing to the needling pain, only 59 cases [out of more than 100] were willing to accept the treatment for a complete course [10 to 15 sessions, undertaken either every day or every other day] or longer.”
3.  About the effectiveness of scalp acupuncture in clinical practice
In a general review of acupuncture therapy (5), it was said that: “Clinical reports of 2,917 cases of hemiplegia treated in 34 units [clinics] reveal an effective rate of 94.5%, with 58.9% markedly improved....Observation of the graphic [EEG] changes of amplitude, decrease of frequency, decrease of the angle of the main peak, deepening of the valley of the wave indicate that scalp needling dilates blood vessels, improves vascular elasticity, reinforces cardiac contraction, and increases cerebral blood flow.”
A problem with claimed effectiveness rates for scalp acupuncture is that there is rarely a control group (or one that is well-matched) to help sort out improvements that might occur spontaneously or due to other therapeutic measures (such as ordinary physical therapy) that might be undertaken.  However, there may be some benefit to examining the disorders that have been treated by this method and the extent of improvements, whatever the cause, that were noted during the treatment period.
In the article by Chen and Chen regarding enuresis treatment (4), effectiveness was moderate (only 9 out of 59 were cured), but it was said that: “It seemed to be a general rule that older children were apt to have better curative results; treatment in the afternoon seemed to be better than in the morning, and a longer time of needle retention was better than short time needle retention....A stronger stimulation often brought about better curative effects.”
In an article on scalp acupuncture for hemiplegia (6), Wang and his colleagues reported that of 110 cases, 29 were essentially cured, with mobility of limbs recovered.  They state that: “Analysis of the 110 cases showed that the location, number and extent of the cerebral lesions correlated closely with the therapeutic effects, and early institution of the acupuncture treatment led to better results....Among 29 cases that were essentially cured, most involved lesions in the external capsule or cerebral lobes, with some single lesions in the internal capsule or brain stem.  However, the 5 ineffective cases had mostly multiple lesions in the basal ganglia, the brain stem, and cerebral ventricles.” 
In an article by Cui Yunmeng (7), scalp acupuncture for facial paralysis was described.  It was reported that 71 out of 100 cases were cured, using 5–40 treatment sessions, given once daily.
In a report on pseudobulbar paralysis (8), Qu Hong, Ren Liping, and Guo Yi describe their results of combining scalp acupuncture and body acupuncture: “The treatment was effective in all 28 cases.  19 cases (68%) were cured and 9 cases (32%) were markedly effective.  The shortest course of treatment was 4 sessions and the longest 4 courses [40 sessions]....The patients in this series were all difficult cases of pseudobulbar paralysis refractory to western and Chinese drugs.  The good therapeutic effects indicated the superiority of this modality.”
A study by Wan Zhijie and colleagues on the mechanism of action of scalp acupuncture (17) indicates that cholinesterase is inhibited and, at the same time, muscle force of the extremities is increased. Further, microcirculation is notably enhanced.  In treating hemiplegia, a single treatment (about 25 minutes, including insertion, three sessions of 3-minute twirling with two 5-minutes breaks, and withdrawal of the needles) muscle strength in upper and lower extremities improved by about 20%, whole blood cholinesterase was reduced by about 15%, and speed of blood flow through nail bed capillaries increased by over 30%.  These changes slowly reverted after treatment to reach pretreatment values after 24 hours, confirming the need for daily scalp acupuncture therapy.
Two reports on aphasia (inability to speak) were presented in the Shanghai Journal of Acupuncture and Moxibustion.  In one report, from the Guangdong Provincial Hospital, 72 cases of stroke-caused aphasia were treated and evaluated (19).  The zones selected were from the “speaking zones” (from a different set of zones than used in Zhu’s scalp acupuncture).  After applying the needles and getting the qi reaction, the needles were hooked up to an electroacupuncture device and stimulated for 20 minutes (once per day).  In addition, body acupuncture was applied (mainly GB-20 on one day and GV-16 on the alternate day, with some non-standard, “extra points”).  Those needles were stimulated for about 20 seconds and then retained for 30 minutes (once per day).  After 30 days of treatment, 46% of the patients showed marked improvement, and another 50% showed some improvement.  In the other report (20), from the Central Hospital of Shantou City (also in Guangdong), aphasia in nine children ages 16 months to 14 years was treated.  The causes were numerous, including viral encephalitis and meningitis.  The speaking zone was treated as the main therapy, and as an adjunct a treatment comprised of needling GV-20, GV-24 and the four points of Sishencong (Extra-6) were treated.  Three needles were used in the speaking zone, they were twirled rapidly for two minutes, then connected to an electroacupuncture device and stimulated for 30 minutes (at 14 Hz).  Treatment lasted from 4–21 days.  Of the 9 patients treated, 4 were reported recovered and 2 improved.
According to the content of these reports, compared to Zhu’s techniques there is shorter duration of individual treatments, reliance on electroacupuncture as stimulation, and no mentioned focus on patient breathing or movements during treatment (e.g., for aphasia, Dr. Zhu needles Eding zone #1 and has the person try to count from 1 to 10, say their address, sing, etc., to use both voice and memory).
4. About the mechanism of action for stroke
In a study of scalp acupuncture applied immediately following a stroke (21), it was reported that both thromboxane B2 (TXB2) and 6-ketone prostaglandin F10 (6KP) levels in the blood plasma were affected.  These biochemicals are the stable metabolites of substances involved in platelet clumping: thromboxane A2, which induces clumping of platelets and contraction of arteries, and prostaglandin I2, which inhibits platelet clumping and inhibits formation of arterial atheromas (by reducing cell proliferation).
The physicians treated 20 patients who had suffered a stroke within the prior 10 days.  For scalp acupuncture, the major areas selected were the “motion” zone and the “diastole-systole” zone.  Body points were also needled; alternating from one day to the next between treatment of yang meridians (points would be selected from LI-15, LI-11, LI-4, TB-5, GB-30, GB-34, GB-39, or UB-60) and treatment of the yin meridians (points would be selected from HT-1, LU-5 PC-6, SI-13, SP-6, or LV-3).  The scalp needles were strongly stimulated with twirling at 200 times per minute for 2–3 minutes, and followed by the lifting maneuver to get the full qi reaction.  Body points were stimulated less, but it was important to get a qi reaction.  Needle retention was for 30 minutes, with electrostimulation used after getting the qi reaction.  Treatment was carried out for 6 consecutive days, followed by a 1 day rest, as one course of treatment, for a total of 4 courses (one month).  Drugs that might affect thromboxane or prostaglandin levels were discontinued prior to the study. 
It was shown that stroke patients had higher plasma TXB2 levels and lower plasma 6KP levels than healthy persons.  After performing acupuncture on the stroke patients, the TXB2 levels declined and the 6KP levels rose.  The changes were statistically significant, though the parameters did not reach the levels of healthy patients.  The improvements in TXB-6KP levels were interpreted as a biochemical manifestation of harmonizing yin and yang.  The authors thought that the effect of acupuncture was mediated by the cerebral cortex and the nervous humoral system.